• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

用于痕量挥发性有机化合物筛查的廉价简易人体呼气采集系统,采用热解吸-气相色谱-质谱联用技术。

Cheap and easy human breath collection system for trace volatile organic compounds screening using thermal desorption - gas chromatography mass spectrometry.

作者信息

Vicent-Claramunt Adrian, Naujalis Evaldas

机构信息

State Research Institute Center for Physical Sciences and Technology, Savanorių Ave. 231, LT-02300Vilnius, Lithuania.

出版信息

MethodsX. 2021 May 14;8:101386. doi: 10.1016/j.mex.2021.101386. eCollection 2021.

DOI:10.1016/j.mex.2021.101386
PMID:34430282
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8374488/
Abstract

•By analyzing the VOCs presents in our breath, we could identify if some components should not be present in our bodies, or their concentration is higher or lower than normal.•To collect breath samples for VOC analysis, we looked into the current available methodologies and, due to their high prices, tried to develop our own easy and cheap device. A simple single use Minigrip LDPE plastic bag was used in this work and its efficiency and performance were tested.•After breath collection, samples were analyzed using Thermal Desorption (TD) system, coupled with Gas Chromatography Mass Spectrometer (GC-MS).

摘要

•通过分析我们呼出气体中存在的挥发性有机化合物(VOCs),我们可以确定某些成分是否不应存在于我们体内,或者它们的浓度是高于还是低于正常水平。

•为了收集用于VOC分析的呼气样本,我们研究了当前可用的方法,由于其价格高昂,我们试图开发自己的简易且廉价的设备。本研究使用了一个简单的一次性迷你握把低密度聚乙烯(LDPE)塑料袋,并测试了其效率和性能。

•收集呼气样本后,使用热脱附(TD)系统结合气相色谱 - 质谱联用仪(GC - MS)对样本进行分析。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bee8/8374488/55f0b028f760/gr17.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bee8/8374488/578a38c0d9a6/fx1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bee8/8374488/4549c74187c3/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bee8/8374488/57f334524c8a/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bee8/8374488/7a80555ce77e/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bee8/8374488/6b0466c5f5bf/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bee8/8374488/431a22b9d6f9/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bee8/8374488/fac10d4d7e21/gr6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bee8/8374488/ab34292a648e/gr7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bee8/8374488/6cd34a2aef7a/gr8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bee8/8374488/52a97ba889b8/gr9.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bee8/8374488/a638445280a1/gr10.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bee8/8374488/079fe1cc77c6/gr11.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bee8/8374488/ff07418576c3/gr12.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bee8/8374488/2187c2ab9cea/gr13.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bee8/8374488/e81e0a825a2a/gr14.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bee8/8374488/2a1a9fb3aaaa/gr15.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bee8/8374488/27b8a4c88cbf/gr16.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bee8/8374488/55f0b028f760/gr17.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bee8/8374488/578a38c0d9a6/fx1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bee8/8374488/4549c74187c3/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bee8/8374488/57f334524c8a/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bee8/8374488/7a80555ce77e/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bee8/8374488/6b0466c5f5bf/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bee8/8374488/431a22b9d6f9/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bee8/8374488/fac10d4d7e21/gr6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bee8/8374488/ab34292a648e/gr7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bee8/8374488/6cd34a2aef7a/gr8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bee8/8374488/52a97ba889b8/gr9.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bee8/8374488/a638445280a1/gr10.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bee8/8374488/079fe1cc77c6/gr11.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bee8/8374488/ff07418576c3/gr12.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bee8/8374488/2187c2ab9cea/gr13.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bee8/8374488/e81e0a825a2a/gr14.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bee8/8374488/2a1a9fb3aaaa/gr15.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bee8/8374488/27b8a4c88cbf/gr16.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bee8/8374488/55f0b028f760/gr17.jpg

相似文献

1
Cheap and easy human breath collection system for trace volatile organic compounds screening using thermal desorption - gas chromatography mass spectrometry.用于痕量挥发性有机化合物筛查的廉价简易人体呼气采集系统,采用热解吸-气相色谱-质谱联用技术。
MethodsX. 2021 May 14;8:101386. doi: 10.1016/j.mex.2021.101386. eCollection 2021.
2
Investigation of different approaches for exhaled breath and tumor tissue analyses to identify lung cancer biomarkers.探索用于呼出气体和肿瘤组织分析以识别肺癌生物标志物的不同方法。
Heliyon. 2020 Jun 17;6(6):e04224. doi: 10.1016/j.heliyon.2020.e04224. eCollection 2020 Jun.
3
Analysis of volatile organic compounds in the breath of patients with stable or acute exacerbation of chronic obstructive pulmonary disease.分析稳定期或慢性阻塞性肺疾病急性加重期患者呼出气中的挥发性有机化合物。
J Breath Res. 2018 Mar 6;12(3):036002. doi: 10.1088/1752-7163/aaa4c5.
4
Analysis of human breath samples using a modified thermal desorption: gas chromatography electrospray ionization interface.使用改良热脱附:气相色谱电喷雾电离接口对人体呼吸样本进行分析。
J Breath Res. 2014 Sep;8(3):037105. doi: 10.1088/1752-7155/8/3/037105. Epub 2014 Sep 4.
5
Evidence of endogenous volatile organic compounds as biomarkers of diseases in alveolar breath.内源性挥发性有机化合物作为肺泡呼出气中疾病生物标志物的证据。
Ann Pharm Fr. 2013 Jul;71(4):203-15. doi: 10.1016/j.pharma.2013.05.002. Epub 2013 Jun 17.
6
A dual center study to compare breath volatile organic compounds from smokers and non-smokers with and without COPD.一项双中心研究,旨在比较吸烟者与不吸烟者、患有慢性阻塞性肺疾病(COPD)者与未患COPD者呼出的挥发性有机化合物。
J Breath Res. 2016 Apr 15;10(2):026006. doi: 10.1088/1752-7155/10/2/026006.
7
[Target and non-target screening of volatile organic compounds in industrial exhaust gas using thermal desorption-gas chromatography-mass spectrometry].[采用热脱附-气相色谱-质谱联用技术对工业废气中挥发性有机化合物进行目标与非目标筛查]
Se Pu. 2017 Oct 8;35(10):1094-1099. doi: 10.3724/SP.J.1123.2017.06023.
8
Proton-transfer reaction mass spectrometry (PTRMS) in combination with thermal desorption (TD) for sensitive off-line analysis of volatiles.质子转移反应质谱(PTRMS)结合热脱附(TD)用于挥发性物质的灵敏离线分析。
Rapid Commun Mass Spectrom. 2012 Apr 30;26(8):990-6. doi: 10.1002/rcm.6191.
9
Common Strategies and Factors Affecting Off-Line Breath Sampling and Volatile Organic Compounds Analysis Using Thermal Desorption-Gas Chromatography-Mass Spectrometry (TD-GC-MS).影响使用热脱附-气相色谱-质谱联用技术(TD-GC-MS)进行离线呼吸采样和挥发性有机化合物分析的常见策略及因素
Metabolites. 2022 Dec 21;13(1):8. doi: 10.3390/metabo13010008.
10
Effects of high relative humidity and dry purging on VOCs obtained during breath sampling on common sorbent tubes.高湿度和干燥吹扫对常用吸附管中呼气采样时 VOCs 的影响。
J Breath Res. 2020 Jul 21;14(4):046006. doi: 10.1088/1752-7163/ab7e17.

引用本文的文献

1
Noninvasive Total Cholesterol Level Measurement Using an E-Nose System and Machine Learning on Exhaled Breath Samples.使用电子鼻系统和机器学习对呼出气体样本进行无创总胆固醇水平测量。
ACS Sens. 2024 Dec 27;9(12):6630-6637. doi: 10.1021/acssensors.4c02198. Epub 2024 Nov 22.

本文引用的文献

1
Profile of exhaled-breath volatile organic compounds to diagnose pancreatic cancer.呼气挥发性有机化合物谱诊断胰腺癌。
Br J Surg. 2018 Oct;105(11):1493-1500. doi: 10.1002/bjs.10909. Epub 2018 Jul 18.
2
Optimisation of sampling parameters for standardised exhaled breath sampling.标准化呼气采样的采样参数优化
J Breath Res. 2017 Dec 6;12(1):016007. doi: 10.1088/1752-7163/aa8a46.
3
Factors that influence the volatile organic compound content in human breath.影响人体呼出气体中挥发性有机化合物含量的因素。
J Breath Res. 2017 Feb 22;11(1):016013. doi: 10.1088/1752-7163/aa5cc5.
4
VOC breath biomarkers in lung cancer.肺癌中的挥发性有机化合物呼吸生物标志物
Clin Chim Acta. 2016 Aug 1;459:5-9. doi: 10.1016/j.cca.2016.05.013. Epub 2016 May 21.
5
Comparison of sampling bags for the analysis of volatile organic compounds in breath.用于分析呼出气体中挥发性有机化合物的采样袋的比较
J Breath Res. 2015 Dec 14;9(4):047110. doi: 10.1088/1752-7155/9/4/047110.
6
The human volatilome: volatile organic compounds (VOCs) in exhaled breath, skin emanations, urine, feces and saliva.人体挥发物组:呼出气、皮肤散发物、尿液、粪便和唾液中的挥发性有机化合物(VOCs)
J Breath Res. 2014 Sep;8(3):034001. doi: 10.1088/1752-7155/8/3/034001. Epub 2014 Jun 19.
7
A review of the volatiles from the healthy human body.健康人体挥发物综述。
J Breath Res. 2014 Mar;8(1):014001. doi: 10.1088/1752-7155/8/1/014001. Epub 2014 Jan 13.
8
Suitability of different polymer bags for storage of volatile sulphur compounds relevant to breath analysis.不同聚合物袋用于储存与呼吸分析相关的挥发性硫化合物的适用性。
J Chromatogr B Analyt Technol Biomed Life Sci. 2009 Jan 15;877(3):189-96. doi: 10.1016/j.jchromb.2008.12.003. Epub 2008 Dec 9.
9
Personal exposure to volatile organic compounds. I. Direct measurements in breathing-zone air, drinking water, food, and exhaled breath.个人对挥发性有机化合物的暴露。I. 呼吸带空气、饮用水、食物和呼出气体中的直接测量。
Environ Res. 1984 Oct;35(1):293-319. doi: 10.1016/0013-9351(84)90137-3.