Westphal Kinga, Dudzik Danuta, Waszczuk-Jankowska Małgorzata, Graff Beata, Narkiewicz Krzysztof, Markuszewski Michał Jan
Department of Hypertension and Diabetology, Medical University of Gdansk, 80-214 Gdansk, Poland.
Department of Biopharmaceutics and Pharmacodynamics, Faculty of Pharmacy, Medical University of Gdansk, 80-416 Gdansk, Poland.
Metabolites. 2022 Dec 21;13(1):8. doi: 10.3390/metabo13010008.
An analysis of exhaled breath enables specialists to noninvasively monitor biochemical processes and to determine any pathological state in the human body. Breath analysis holds the greatest potential to remold and personalize diagnostics; however, it requires a multidisciplinary approach and collaboration of many specialists. Despite the fact that breath is considered to be a less complex matrix than blood, it is not commonly used as a diagnostic and prognostic tool for early detection of disordered conditions due to its problematic sampling, analysis, and storage. This review is intended to determine, standardize, and marshal experimental strategies for successful, reliable, and especially, reproducible breath analysis.
对呼出气体的分析使专家能够以非侵入性方式监测生化过程并确定人体的任何病理状态。呼吸分析在重塑诊断和个性化诊断方面具有最大潜力；然而，它需要多学科方法以及众多专家的协作。尽管呼出气体被认为是比血液更简单的基质，但由于其采样、分析和储存存在问题，它并不常用于早期检测疾病状况的诊断和预后工具。本综述旨在确定、规范和整理成功、可靠且尤其是可重复的呼吸分析的实验策略。
