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西班牙 COVID-19 大流行期间非洲社区简化乙肝病毒检测的新型护理模式。

A novel model of care for simplified testing of HBV in African communities during the COVID-19 pandemic in Spain.

机构信息

Barcelona Institute for Global Health (ISGlobal), Hospital Clínic, University of Barcelona, Barcelona, Spain.

Department of Health, Center for Epidemiological Studies on Sexually Transmitted Infections and HIV/AIDS in Catalonia (CEEISCAT), Generalitat of Catalonia, Badalona, Spain.

出版信息

Sci Rep. 2021 Aug 25;11(1):17063. doi: 10.1038/s41598-021-96350-3.

Abstract

Chronic hepatitis B virus (HBV) infection is a major public health threat for migrant populations in Spain and efforts to scale up testing are needed to reach the WHO elimination targets. The Hepatitis B Virus Community Screening and Vaccination in Africans (HBV-COMSAVA) study aims to use point-of-care testing and simplified diagnostic tools to identify, link to care, or vaccinate African migrants in Barcelona during the COVID-19 pandemic. From 21/11/20 to 03/07/2021, 314 study participants were offered HBV screening in a community clinic. Rapid tests for HBsAg screening were used and blood samples were collected with plasma separation cards. Patients received results and were offered: linkage to specialist care; post-test counselling; or HBV vaccination in situ. Sociodemographic and clinical history were collected and descriptive statistics were utilized. 274 patients were included and 210 (76.6%) returned to receive results. The HBsAg prevalence was 9.9% and 33.2% of people had evidence of past resolved infection. Overall, 133 required vaccination, followed by post-test counselling (n = 114), and linkage to a specialist (n = 27). Despite the COVID-19 pandemic, by employing a community-based model of care utilizing novel simplified diagnostic tools, HBV-COMSAVA demonstrated that it was possible to diagnose, link to care, and vaccinate African migrants in community-based settings.

摘要

慢性乙型肝炎病毒(HBV)感染是西班牙移民群体面临的主要公共卫生威胁,需要加大检测力度,以实现世界卫生组织消除目标。乙型肝炎病毒社区筛查和接种非洲人(HBV-COMSAVA)研究旨在利用即时检测和简化的诊断工具,在 COVID-19 大流行期间,在巴塞罗那为非洲移民进行 HBV 筛查、建立联系或接种疫苗。2020 年 11 月 21 日至 2021 年 7 月 3 日,314 名研究参与者在社区诊所接受 HBV 筛查。使用 HBsAg 快速检测进行筛查,并使用血浆分离卡采集血样。患者会收到检测结果,并提供以下三种选择:与专科医生建立联系、接受检测后咨询、或现场接种乙肝疫苗。收集了社会人口统计学和临床病史,并利用描述性统计进行分析。共纳入 274 名患者,其中 210 名(76.6%)返回诊所接收结果。HBsAg 的流行率为 9.9%,33.2%的人有既往感染已恢复的证据。总的来说,有 133 人需要接种疫苗,其次是检测后咨询(n=114),以及与专科医生建立联系(n=27)。尽管面临 COVID-19 大流行,但是通过采用社区为基础的护理模式,并利用新型简化诊断工具,HBV-COMSAVA 表明,在社区环境中,对非洲移民进行诊断、建立联系和接种疫苗是可行的。

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