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使用双作用环和注射涂抹器递送的局部麻醉剂可减轻羔羊断尾时的急性疼痛反应。

Local Anesthetic Delivered with a Dual Action Ring and Injection Applicator Reduces the Acute Pain Response of Lambs during Tail Docking.

作者信息

Small Alison, Marini Danila, Colditz Ian

机构信息

CSIRO Agriculture and Food, Armidale, NSW 2350, Australia.

出版信息

Animals (Basel). 2021 Jul 30;11(8):2242. doi: 10.3390/ani11082242.

DOI:10.3390/ani11082242
PMID:34438699
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8388468/
Abstract

Docking the tail of lambs is a standard husbandry procedure and is achieved through several techniques including clamps, hot or cold knives and latex rings, the last of which is the most popular. All tail docking methods cause acute pain which can be reduced by application of local anesthetic, however precise anatomical injection for optimal efficacy requires considerable skill. This pen trial evaluated the ability of local anesthetic (LA) delivered with a dual function ring applicator/injector to alleviate acute tail docking pain. Thirty ewe lambs were assigned to one of three treatment groups ( = 10 per group): ring plus local anesthetic (Ring LA), ring only (Ring) and sham handled control (Sham). Lambs were videoed and their behavior categorized every five minutes for the first hour and every 10 min for the subsequent two hours after treatment. There was a significant effect ( < 0.001) of treatment on total active pain related behaviors in the first hour, with Ring lambs showing higher counts compared to Ring LA or Sham. Ring lambs also displayed a significantly higher count of combined abnormal postures ( < 0.001) than Ring LA or Sham lambs. Delivery of 1.5 mL of 2% lignocaine via the dual action device abolished abnormal behaviors and signs of pain in Ring LA lambs. However, lambs in the Ring LA group spent less time attempting to suckle compared to Ring and Sham lambs, suggesting that some residual discomfort remained.

摘要

给羔羊断尾是一种标准的饲养管理程序,可通过多种技术实现,包括使用夹子、热刀或冷刀以及乳胶环,其中乳胶环是最常用的。所有断尾方法都会引起急性疼痛,局部麻醉可减轻这种疼痛,然而,为达到最佳效果进行精确的解剖学注射需要相当高的技巧。本围栏试验评估了使用具有双重功能的环式涂抹器/注射器递送局部麻醉剂(LA)减轻断尾急性疼痛的能力。将30只母羊羔分为三个治疗组之一(每组 = 10只):环加局部麻醉剂(环LA)、仅使用环(环)和假处理对照组(假)。在处理后的第一个小时内,每五分钟对羊羔进行录像并对其行为进行分类,在随后的两个小时内每十分钟进行一次分类。在第一个小时内,治疗对与总主动疼痛相关行为有显著影响(P < 0.001),与环LA或假处理组相比,仅使用环组的羊羔表现出更高的计数。仅使用环组的羊羔还表现出比环LA或假处理组的羊羔显著更高的异常姿势组合计数(P < 0.001)。通过双功能装置递送1.5 mL 2%的利多卡因消除了环LA组羊羔的异常行为和疼痛迹象。然而,与仅使用环组和假处理组的羊羔相比,环LA组的羊羔尝试吸吮的时间较少,这表明仍存在一些残留不适。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed61/8388468/c83506f53b28/animals-11-02242-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed61/8388468/aec107c4042a/animals-11-02242-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed61/8388468/abccbac625be/animals-11-02242-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed61/8388468/c83506f53b28/animals-11-02242-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed61/8388468/aec107c4042a/animals-11-02242-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed61/8388468/abccbac625be/animals-11-02242-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed61/8388468/c83506f53b28/animals-11-02242-g003.jpg

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本文引用的文献

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Res Vet Sci. 2020 Dec;133:210-218. doi: 10.1016/j.rvsc.2020.09.025. Epub 2020 Oct 2.
2
A randomised field study evaluating the effectiveness of buccal meloxicam and topical local anaesthetic formulations administered singly or in combination at improving welfare of female Merino lambs undergoing surgical mulesing and hot knife tail docking.一项随机现场研究,评估单独或联合使用颊部美洛昔康和局部麻醉剂配方对改善接受外科去势和热刀断尾的美利奴母羊福利的有效性。
Res Vet Sci. 2018 Jun;118:305-311. doi: 10.1016/j.rvsc.2018.03.006. Epub 2018 Mar 8.
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Animals (Basel). 2023 Apr 15;13(8):1358. doi: 10.3390/ani13081358.
4
Sex impacts pain behaviour but not emotional reactivity of lambs following ring tail docking.性别会影响羔羊断尾后疼痛行为,但不会影响其情绪反应。
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Development and Application of a High-Resolution Melting Analysis with Unlabeled Probes for the Screening of Short-Tailed Sheep Heterozygotes.一种用于筛选短尾羊杂合子的无标记探针高分辨率熔解分析方法的开发与应用。
Animals (Basel). 2022 Mar 21;12(6):792. doi: 10.3390/ani12060792.
A pen study evaluation of buccal meloxicam and topical anaesthetic at improving welfare of lambs undergoing surgical mulesing and hot knife tail docking.一项关于颊部应用美洛昔康和局部麻醉剂对改善接受外科去势术和热刀断尾术羔羊福利的围栏试验评估。
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