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Optimal selection of asymptomatic patients for carotid endarterectomy based on predicted 5-year survival.基于预测的 5 年生存率对无症状患者进行颈动脉内膜切除术的最佳选择。
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无症状性颈动脉狭窄的管理:对老年患者进行手术有好处吗?

The management of asymptomatic carotid stenosis: Is there a benefit to operate elderly patients?

作者信息

Bouayed N M, Sekkal A

机构信息

University hospital Hai Sabah 31000 - Oran Algeria.

出版信息

Transl Med UniSa. 2020 Oct 1;23:79-81. doi: 10.37825/2239-9747.1017. eCollection 2020 Sep.

DOI:10.37825/2239-9747.1017
PMID:34447720
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8370528/
Abstract

BACKGROUND

We present a retrospective study of a series of 40 patients over the age of 75 operated for an asymptomatic carotid stenosis. The results were evaluated during an average of 3 years of follow-up.

MATERIAL AND METHOD

The study is retrospective and monocentric. The series includes 40 patients aged over 75 years and with an average age of 78.5 years (range 75-82). Patients underwent surgery for an asymptomatic carotid stenosis of more than 80%. The technique in all case was a carotid endarterectomy.

RESULTS

There have been no postoperative deaths or neurological adverse events. During an average follow-up of 3 years, there was one death secondary to colon cancer. However, 5 patients were lost to follow-up.

CONCLUSION

Carotid surgery in elderly patients may have a benefit. However, our study has shortcomings. It is retrospective and the patient cohort is reduced. A randomized, prospective study, comparing surgery or angioplasty with the best medical treatment, is necessary to choose the most effective and safest treatment to offer to an elderly patient with asymptomatic carotid stenosis.

摘要

背景

我们对40例年龄超过75岁的无症状性颈动脉狭窄患者进行了一项回顾性研究。在平均3年的随访期间对结果进行了评估。

材料与方法

本研究为回顾性单中心研究。该系列包括40例年龄超过75岁的患者,平均年龄为78.5岁(范围75 - 82岁)。患者因无症状性颈动脉狭窄超过80%接受手术治疗。所有病例均采用颈动脉内膜切除术。

结果

术后无死亡病例及神经不良事件发生。在平均3年的随访期间,有1例死于结肠癌。然而,有5例患者失访。

结论

老年患者行颈动脉手术可能有益。然而,我们的研究存在不足。它是回顾性的且患者队列数量较少。有必要进行一项随机、前瞻性研究,比较手术或血管成形术与最佳药物治疗,以选择为老年无症状性颈动脉狭窄患者提供最有效和最安全的治疗方法。