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腹腔镜下二极管激光治疗深部子宫内膜异位症:我们的经验。

Laparoscopic treatment of deep endometriosis with a diode laser: our experience.

机构信息

Department of Surgical Sciences, Division of Gynecology and Obstetrics, University of Cagliari, Cagliari, Italy.

Department of Medical and Surgical Sciences, Institute of Obstetrics and Gynecology, University of Foggia, Foggia, Italy.

出版信息

Arch Gynecol Obstet. 2021 Nov;304(5):1221-1231. doi: 10.1007/s00404-021-06154-z. Epub 2021 Aug 26.

Abstract

PURPOSE

To evaluate whether laparoscopic treatment with a diode laser is feasible, safe, and effective in symptomatic patients affected by deep endometriosis (DE).

METHODS

This retrospective study was performed using medical record data. The surgical reports, chronic pain scores, and quality of life (QoL) data were evaluated for 50 patients who had undergone laparoscopic surgery between November 2017 and March 2019 at two university hospitals (Monserrato (CA) and Foggia, Italy). Indications for surgery were chronic pelvic pain and/or infertility in patients who wished to conceive spontaneously. Endometriosis lesions/nodules were excised using a diode laser (Leonardo®, Biolitec® DUAL 45) that can combine 980 and 1470 nm wavelengths transmitted through a 1000 µm conical optical fibre.

RESULTS

The median patient age was 32 years (range 21-44), with a body mass index (BMI) mean of 21.7  ±  2.9 kg/m. The mean operation time was 147 min (range 106-190). No intraoperative or early complications (< 30 days) were reported. All patients left the hospital, on average, within 3 days (range 2-9 days) after surgery. A significant improvement in pain was observed at the 3-, 6-, and 12-month follow-up (p < 0.01) in all patients. Moreover, patients reported a significant QoL improvement at the 12-month follow-up.

CONCLUSION

The diode laser confirmed its feasibility and safety for treating endometriosis. During the shaving surgical procedure, the diode laser system ensures a safe and effective laparoscopic dissection of deep endometriotic lesions. Further comprehensive randomized trials are necessary to confirm these preliminary data in terms of efficacy, recurrence rates, and pregnancy outcomes.

摘要

目的

评估二极管激光腹腔镜治疗深部子宫内膜异位症(DE)的可行性、安全性和有效性。

方法

本回顾性研究使用病历数据进行。评估了 2017 年 11 月至 2019 年 3 月在意大利蒙塞拉特(CA)和福贾的两家大学医院接受腹腔镜手术的 50 名患者的手术报告、慢性疼痛评分和生活质量(QoL)数据。手术指征为有慢性盆腔痛和/或希望自然受孕的不孕患者的子宫内膜异位症病变/结节。使用二极管激光(Leonardo®,Biolitec® DUAL 45)切除子宫内膜异位症病灶/结节,该激光可以结合通过 1000 µm 锥形光纤传输的 980 和 1470nm 波长。

结果

患者年龄中位数为 32 岁(范围 21-44),平均体重指数(BMI)为 21.7±2.9kg/m2。手术平均时间为 147 分钟(范围 106-190)。无术中或早期(<30 天)并发症报告。所有患者平均在手术后 3 天(范围 2-9 天)内出院。所有患者在 3、6 和 12 个月随访时疼痛均显著改善(p<0.01)。此外,患者在 12 个月随访时报告 QoL 显著改善。

结论

二极管激光证实了其治疗子宫内膜异位症的可行性和安全性。在刮除手术过程中,二极管激光系统可确保安全有效地进行深部子宫内膜异位症病变的腹腔镜分离。需要进一步的全面随机试验来确认这些初步数据在疗效、复发率和妊娠结局方面的有效性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3a0e/8490256/8eec3c172e97/404_2021_6154_Fig1_HTML.jpg

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