Ercoli Alfredo, Bassi Emma, Ferrari Stefania, Surico Daniela, Fagotti Anna, Fanfani Francesco, De Cicco Fiorenzo, Surico Nicola, Scambia Giovanni
Department of Obstetrics and Gynecology, Maggiore della Carità Hospital, Università del Piemonte Orientale, Novara, Italy.
Department of Gynecologic Surgery, Policlinico Abano Terme, Abano Terme, Italy.
J Minim Invasive Gynecol. 2017 Jul-Aug;24(5):863-868. doi: 10.1016/j.jmig.2017.03.011. Epub 2017 Mar 18.
Deep infiltrating endometriosis (DIE) is a complex disease that impairs the quality of life and the fertility of women. Colorectal DIE accounts for 70% to 93% of all the intestinal endometriotic sites and frequently needs a surgical approach. However, the indications for the surgical management of this condition are still controversial. From March 2010 to June 2014, we scheduled 33 consecutive patients presenting with retrocervical-rectal DIE of any diameter not involving the mucosa nor producing rectal stenosis >50% for laparoscopic robotic-assisted nerve-sparing rectal nodulectomy (LRN). All patients were examined preoperatively, at 3 months and 6 months postoperatively, and yearly thereafter. Dysmenorrhea, dyschezia, dyspareunia, and dysuria were evaluated on a 10-point visual analog scale. Among the 33 enrolled patients, 31 (93.9%) fulfilled the selection criteria and were submitted to LRN. In 1 out of 31 available patients (3.2%), a segmental bowel resection was considered necessary for prudential purpose at the end of the nodulectomy procedure. No laparotomic conversion was performed in any case. A wide variety of associated surgical procedures were performed in 25 of 30 patients (83.3%). No intraoperative complications were observed. One grade 3b and 2 grade 1 postoperative complications were recorded. The mean larger axis of the excised nodules measured on the formalin-fixed specimen was 26.4 mm. We found significant improvements in patient symptoms at a 3-month follow-up which persisted over the time. We observed 2 (6.7%) recurrences of intestinal endometriosis and 1 (3.3%) recurrence of chronic pelvic pain without clinical and/or radiologic evidence of endometriotic lesions. The mean follow-up time was 27.6 months. We believe that LRN is feasible and safe and shows promising results in terms of radicality, anatomic recurrence rate, and pain recurrence rate for treating isolated retrocervical-rectal DIE not involving the mucosa, without limiting this procedure to nodules smaller than 3 cm.
深部浸润型子宫内膜异位症(DIE)是一种复杂疾病,会损害女性的生活质量和生育能力。结直肠DIE占所有肠道子宫内膜异位症部位的70%至93%,常需手术治疗。然而,这种疾病手术治疗的指征仍存在争议。2010年3月至2014年6月,我们连续安排了33例患有宫颈后直肠DIE的患者,其病灶直径不限,未累及黏膜且未导致直肠狭窄超过50%,接受腹腔镜机器人辅助保留神经的直肠结节切除术(LRN)。所有患者在术前、术后3个月和6个月进行检查,此后每年检查一次。痛经、排便困难、性交困难和排尿困难采用10分视觉模拟量表进行评估。在33例入组患者中,31例(93.9%)符合入选标准并接受了LRN。在31例可用患者中的1例(3.2%)中,出于谨慎考虑,在结节切除术后认为有必要进行节段性肠切除。在任何情况下均未进行开腹手术转换。30例患者中的25例(83.3%)进行了各种相关手术。未观察到术中并发症。记录到1例3b级和2例1级术后并发症。在福尔马林固定标本上测量的切除结节的平均最大直径为26.4毫米。我们发现在3个月的随访中患者症状有显著改善,且这种改善随时间持续存在。我们观察到2例(6.7%)肠道子宫内膜异位症复发,1例(3.3%)慢性盆腔疼痛复发,且无子宫内膜异位症病变的临床和/或影像学证据。平均随访时间为27.6个月。我们认为LRN是可行且安全的,在治疗未累及黏膜的孤立性宫颈后直肠DIE方面,在根治性、解剖学复发率和疼痛复发率方面显示出有前景的结果,且不将该手术局限于小于3厘米的结节。