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116539 例 COVID-19 住院患者的特征和临床结局。波兰,2020 年 3 月至 12 月。

Characteristics and Clinical Outcomes of 116,539 Patients Hospitalized with COVID-19-Poland, March-December 2020.

机构信息

Department of Public Health, Medical University of Warsaw, 02-097 Warsaw, Poland.

Centre of Postgraduate Medical Education, School of Public Health, 01-826 Warsaw, Poland.

出版信息

Viruses. 2021 Jul 27;13(8):1458. doi: 10.3390/v13081458.

Abstract

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes Coronavirus Disease 2019 (COVID-19). This study aimed to characterize patients hospitalized with COVID-19 in Poland between March and December 2020, as well as to identify factors associated with COVID 19-related risk of in-hospital death. This retrospective analysis was based on data from the hospital discharge reports on COVID-19 patients hospitalized in Poland between March and December 2020. A total of 116,539 discharge reports on patients hospitalized with COVID-19 were analyzed. Among patients with COVID-19, 21,490 (18.4%) died during hospitalization. Patients over 60 years of age (OR = 7.74; 95%CI: 7.37-8.12; < 0.001), men (OR = 1.42; 95%CI: 1.38-1.47; < 0.001) as well as those with cardiovascular diseases (OR = 1.51; 95%CI: 1.46-1.56; < 0.001) or disease of the genitourinary system (OR = 1.39; 95%CI: 1.31-1.47; < 0.001) had much higher odds of COVID 19-related risk of in-hospital death. The presence of at least one comorbidity more than doubled the COVID 19-related risk of in-hospital death (OR = 2.23; 95%CI: 2.14-2.32; < 0.01). The following predictors of admission to ICU were found in multivariable analysis: age over 60 years (OR: 2.03; 95%CI: 1.90-2.16), male sex (OR: 1.79; 95%CI: 1.69-1.89), presence of at least one cardiovascular disease (OR: 1.26; 95%CI: 1.19-1.34), presence of at least one endocrine, nutritional and metabolic disease (OR: 1.17; 95%CI: 1.07-1.28).

摘要

严重急性呼吸综合征冠状病毒 2 (SARS-CoV-2) 导致 2019 年冠状病毒病 (COVID-19)。本研究旨在描述 2020 年 3 月至 12 月期间在波兰住院的 COVID-19 患者的特征,并确定与 COVID-19 相关的住院死亡风险相关的因素。这项回顾性分析基于 2020 年 3 月至 12 月期间在波兰住院的 COVID-19 患者的出院报告数据。共分析了 116539 份 COVID-19 患者的出院报告。在 COVID-19 患者中,21490 人(18.4%)在住院期间死亡。60 岁以上的患者(OR = 7.74;95%CI: 7.37-8.12;< 0.001)、男性(OR = 1.42;95%CI: 1.38-1.47;< 0.001)以及患有心血管疾病(OR = 1.51;95%CI: 1.46-1.56;< 0.001)或泌尿生殖系统疾病(OR = 1.39;95%CI: 1.31-1.47;< 0.001)的患者,COVID-19 相关住院死亡风险更高。至少存在一种合并症使 COVID-19 相关住院死亡风险增加一倍以上(OR = 2.23;95%CI: 2.14-2.32;< 0.01)。多变量分析发现,以下因素是入住 ICU 的预测因素:60 岁以上年龄(OR: 2.03;95%CI: 1.90-2.16)、男性(OR: 1.79;95%CI: 1.69-1.89)、至少存在一种心血管疾病(OR: 1.26;95%CI: 1.19-1.34)、至少存在一种内分泌、营养和代谢疾病(OR: 1.17;95%CI: 1.07-1.28)。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7655/8402804/c0d59d302f68/viruses-13-01458-g001.jpg

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