临床重要的巴尔通体病毒及其在人体样本中的检测。
Clinically Important Phleboviruses and Their Detection in Human Samples.
机构信息
Arbovirus Reference and Reagent Laboratory, WHO Collaborating Center, Division of Vector Borne Diseases, Centers for Disease Control and Prevention, 3156 Rampart Road-Foothills Research Campus, Fort Collins, CO 80521, USA.
Arbovirus Diagnostic and Reference Team, Division of Vector Borne Diseases, Centers for Disease Control and Prevention, 3156 Rampart Road-Foothills Research Campus, Fort Collins, CO 80521, USA.
出版信息
Viruses. 2021 Jul 30;13(8):1500. doi: 10.3390/v13081500.
The detection of phleboviruses (family: ) in human samples is challenged by the overall diversity and genetic complexity of clinically relevant strains, their predominantly nondescript clinical associations, and a related lack of awareness among some clinicians and laboratorians. Here, we seek to inform the detection of human phlebovirus infections by providing a brief introduction to clinically relevant phleboviruses, as well as key targets and approaches for their detection. Given the diversity of pathogens within the genus, this report focuses on diagnostic attributes that are generally shared among these agents and should be used as a complement to, rather than a replacement of, more detailed discussions on the detection of phleboviruses at the individual virus level.
在人类样本中检测黄病毒（科：）具有挑战性，这是因为临床相关株的总体多样性和遗传复杂性、它们与临床症状之间缺乏明确关联，以及一些临床医生和实验室人员对此缺乏认识。在此，我们旨在通过简要介绍临床相关黄病毒，以及检测它们的关键靶标和方法，为黄病毒感染的检测提供信息。鉴于该属内病原体的多样性，本报告重点介绍了这些病原体之间普遍存在的诊断特征，应将其作为对黄病毒个体水平检测的更详细讨论的补充，而不是替代。
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