Parantainen J, Tenhunen E, Kangasniemi R, Sankari S, Atroshi F
Research Laboratories, Medica Pharmaceutical Co. Ltd, Helsinki, Finland.
Vet Res Commun. 1987;11(5):467-77. doi: 10.1007/BF00380629.
Milk and blood levels of silicon, selenium and the selenoenzyme glutathione peroxidase (GSH-Px) were measured in 20 healthy and 21 mastitic cows. In milk samples from healthy quarters the mean silicon concentration was 0.81 and in affected ones 0.39 ppm. In serum the mean silicon values were 1.63 and 1.02 ppm respectively. The selenium status was not altered but the level of erythrocyte GSH-Px was lowered in mastitic animals. Silicon is known to have marked effects on free radical formation, lipid peroxidation and macrophage activity. Its possible role in infection and inflammation is evaluated. Some of the functions of silicon may resemble those of selenium. The possibility of lowered levels of silicon and of the selenoenzyme in mastitis calls for experimentation with dietary or pharmaceutical supplementation of these trace elements.
