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对印度药物使用障碍患者性功能障碍研究的系统评价。

A systematic review of Indian studies on sexual dysfunction in patients with substance use disorders.

作者信息

Sarkar Siddharth, Chawla Nishtha, Tom Ashlyn, Pandit Prabhat Mani, Sen Mahadev Singh

机构信息

Department of Psychiatry, National Drug Dependence Treatment Centre, All India Institute of Medical Sciences, New Delhi, India.

出版信息

Indian J Psychiatry. 2021 Jul-Aug;63(4):326-334. doi: 10.4103/psychiatry.IndianJPsychiatry_716_20. Epub 2021 Aug 7.

Abstract

BACKGROUND AND AIMS

Sexual dysfunction is often associated with substance use disorders. This study aimed to synthesize Indian literature on sexual dysfunction among patients with substance use disorders.

MATERIALS AND METHODS

Electronic search engines were used to identify studies of the last 20 years that reported sexual dysfunction with different substance use disorders. Information was extracted using a predefined template. Quality appraisal of the included studies was carried out using Joanna Briggs Institute checklist.

RESULTS

Twenty-seven relevant papers were identified that pertained to 24 distinct studies. Most of them were in patients with alcohol dependence, and fewer were in patients with opioid dependence. The study designs were primarily single-group cross-sectional, though many case-control, cross-sectional studies were also identified. The proportion of participants with sexual dysfunction ranged from 22.2% to 76% for studies related to alcohol dependence and 40% to 90% for studies pertaining to opioid dependence. Varied types of sexual dysfunctions were identified, including poor satisfaction, lack of desire, premature ejaculation, and erectile dysfunction. Efforts to address bias and confounders were not reported in most studies.

CONCLUSION

Sexual dysfunction affects a substantial proportion of patients with substance use disorders. Clinicians can make an effort to ascertain and address sexual dysfunction in their routine clinical practice while dealing with patients with substance use disorders.

摘要

背景与目的

性功能障碍常与物质使用障碍相关。本研究旨在综合印度关于物质使用障碍患者性功能障碍的文献。

材料与方法

使用电子搜索引擎检索过去20年中报告不同物质使用障碍患者性功能障碍的研究。使用预定义模板提取信息。采用乔安娜·布里格斯研究所清单对纳入研究进行质量评估。

结果

共识别出27篇相关论文,涉及24项不同研究。其中大多数研究对象为酒精依赖患者,阿片类药物依赖患者的研究较少。研究设计主要为单组横断面研究,不过也识别出许多病例对照、横断面研究。酒精依赖相关研究中性功能障碍参与者的比例在22.2%至76%之间,阿片类药物依赖相关研究中这一比例在40%至90%之间。识别出多种类型的性功能障碍,包括满意度低、性欲缺乏、早泄和勃起功能障碍。大多数研究未报告处理偏倚和混杂因素的措施。

结论

性功能障碍影响相当一部分物质使用障碍患者。临床医生在处理物质使用障碍患者时,可在日常临床实践中努力确定并解决性功能障碍问题。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc08/8363888/80d002b0d839/IJPsy-63-326-g001.jpg

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