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镰状细胞贫血合并十二指肠溃疡穿孔作为一种并发症:何时怀疑这种罕见情况?

Sickle cell anemia with perforated duodenal ulcer as a complication: when to suspect this rare entity?

作者信息

Lopes Raquel Nascimento, Akuri Marina Cristina, da Silva Marília Ferreira Gomes, Puchnick Andrea, Regacini Rodrigo

机构信息

Radiologist resident of the Departament of Radiology - Escola Paulista de Medicina (EPM) - Universidade Federal de São Paulo (UNIFESP), Rua Napoleão de Barros, 800 - São Paulo, SP, Brazil.

Educational and research coordinator of the Departament of Radiology - EPM - UNIFESP, Rua Napoleão de Barros, SP, Brazil.

出版信息

Radiol Case Rep. 2021 Aug 17;16(10):3139-3142. doi: 10.1016/j.radcr.2021.07.039. eCollection 2021 Oct.

DOI:10.1016/j.radcr.2021.07.039
PMID:34457103
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8377549/
Abstract

Perforated duodenal peptic ulcers are often not considered when making a differential diagnosis of abdominal pain, especially in the context of sickle cell disease, and cases have not been frequently described in the literature. This study reports the case of a 14 year-old girl with sickle cell anemia complicated with duodenal ulcer perforation, focusing mainly on the imaging aspects. Abdominal CT should be considered as a method for this diagnosis and it requires the knowledge of this entity and its characteristic imaging findings.

摘要

在对腹痛进行鉴别诊断时,尤其是在镰状细胞病的背景下,常常不会考虑十二指肠消化性溃疡穿孔,并且文献中也未频繁描述此类病例。本研究报告了一名14岁患有镰状细胞贫血并伴有十二指肠溃疡穿孔的女孩的病例,主要聚焦于影像学方面。腹部CT应被视为诊断此疾病的一种方法,并且需要了解该疾病实体及其特征性影像学表现。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/afbd/8377549/44f980c9082d/gr6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/afbd/8377549/722acade0370/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/afbd/8377549/425842151ad6/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/afbd/8377549/60d567b6714e/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/afbd/8377549/069554c2223f/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/afbd/8377549/399712faed24/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/afbd/8377549/44f980c9082d/gr6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/afbd/8377549/722acade0370/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/afbd/8377549/425842151ad6/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/afbd/8377549/60d567b6714e/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/afbd/8377549/069554c2223f/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/afbd/8377549/399712faed24/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/afbd/8377549/44f980c9082d/gr6.jpg

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Radiol Case Rep. 2021 Aug 17;16(10):3139-3142. doi: 10.1016/j.radcr.2021.07.039. eCollection 2021 Oct.
2
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引用本文的文献

1
Sequential gastric and ileal perforations, a rare presentation in a man with sickle cell anemia: A case report.顺序性胃和回肠穿孔,镰状细胞贫血男性患者的罕见表现:一例报告
J Int Med Res. 2025 May;53(5):3000605251343290. doi: 10.1177/03000605251343290. Epub 2025 May 24.

本文引用的文献

1
Duodenal perforation: an unusual complication of sickle cell anemia.十二指肠穿孔:镰状细胞贫血的一种罕见并发症。
Pan Afr Med J. 2014 Jul 16;18:217. doi: 10.11604/pamj.2014.18.217.4645. eCollection 2014.
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Abdominal pain in children with sickle cell disease.儿童镰状细胞病的腹痛。
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Constipation as cause of acute abdominal pain in children.便秘作为儿童急性腹痛的病因
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Gastroduodenal peptic ulcer and Helicobacter pylori infection in children and adolescents.儿童和青少年的胃十二指肠消化性溃疡与幽门螺杆菌感染
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