Acıpayam Can, Aldıç Güliz, Akçora Bülent, Çelikkaya Mehmet Emin, Aşkar Hasan, Dorum Bayram Ali
Mustafa Kemal University, School of Medicine, Department of Pediatric Hematology and Oncology, Hatay, Turkey.
Mustafa Kemal University, School of Medicine, Department of Pediatrics, Hatay, Turkey.
Pan Afr Med J. 2014 Jul 16;18:217. doi: 10.11604/pamj.2014.18.217.4645. eCollection 2014.
Duodenal perforation in childhood is a rare condition with a high mortality rate if not treated surgically. Primary gastroduodenal perforation is frequently associated with peptic ulcer and exhibits a positive family history. Helicobacter pylorus is the most significant agent. Secondary gastroduodenal perforation may be a finding of specific diseases, such as Crohn disease, or more rarely may be associated with diseases such as cystic fibrosis or sickle cell anemia. A 14-year-old boy presented with abdominal and back pain. The patient was operated on for acute abdomen and diagnosed with duodenal perforation. Helicobacter pylorus was negative. There was no risk factor to account for duodenal perforation other than sickle cell anemia. Surgical intervention was successful and without significant sequelae. Duodenal perforation is a rare entity described in patients with sickle cell anemia. To our knowledge, this is the first report of duodenal perforation in a patient sickle cell anemia.
儿童十二指肠穿孔是一种罕见疾病，若不进行手术治疗，死亡率很高。原发性胃十二指肠穿孔常与消化性溃疡相关，且有阳性家族史。幽门螺杆菌是最重要的致病因素。继发性胃十二指肠穿孔可能是某些特定疾病的表现，如克罗恩病，或更罕见地与囊性纤维化或镰状细胞贫血等疾病相关。一名14岁男孩出现腹痛和背痛。该患者因急腹症接受手术，被诊断为十二指肠穿孔。幽门螺杆菌检测为阴性。除镰状细胞贫血外，没有其他导致十二指肠穿孔的危险因素。手术干预成功，且无明显后遗症。十二指肠穿孔是镰状细胞贫血患者中描述的一种罕见病症。据我们所知，这是镰状细胞贫血患者发生十二指肠穿孔的首例报告。
