Kudela Erik, Kajo Karol, Kozubik Erik, Rokos Tomas, Pribulova Terezia, Danko Jan, Kudelova Eva, Homola Igor, Slavik Pavol, Macurova Barbora, Biringer Kamil
Department of Obstetrics & Gynecology, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, Slovakia.
Department of Pathology, St. Elisabeth Cancer Institute, 812 50 Bratislava, Slovakia.
Case Rep Obstet Gynecol. 2021 Aug 19;2021:2476691. doi: 10.1155/2021/2476691. eCollection 2021.
Phyllodes tumors (PTs) are rare fibroepithelial neoplasms of the breast. They have a proliferating stromal component that can be graded as benign, borderline, and malignant. In addition, they are associated with an increased risk of local recurrence and distant metastasis. The authors hereby present a case report of a 34-year-old woman with recurrent malignant PT with an increasing aggressiveness. There were two recurrences of giant tumors that consumed the entire right breast, which developed over a three-year period. The final surgical treatment was a total extirpation of the tumor with subsequent plastic reconstruction using a cutaneous flap from the region of the latissimus dorsi muscle. The patient died three months after the last recurrence due to multiorgan failure.
叶状肿瘤（PTs）是一种罕见的乳腺纤维上皮性肿瘤。它们具有增殖性的间质成分，可分为良性、交界性和恶性。此外，它们与局部复发和远处转移风险增加相关。作者在此报告一例34岁女性复发性恶性PT且侵袭性增加的病例。巨大肿瘤复发两次，在三年时间里累及整个右乳。最终手术治疗是肿瘤全切，随后使用背阔肌区域的皮瓣进行整形重建。患者在最后一次复发三个月后因多器官衰竭死亡。
