乳腺恶性叶状肿瘤伴快速进展：1例报告
Malignant phyllodes tumor of the breast with rapid progression: a case report.
作者信息
Abe Hajime, Teramoto Atsuko, Takei Yumiko, Tanaka Yoshihito, Yoneda Genichiro
机构信息
Breast Center, Bell Land General Hospital, 500-3 Higashiyama, Naka-ku, Sakai, Osaka, 599-8247, Japan.
Department of Breast Surgery, Kansai Medical University Kori Hospital, 8-45, Kori-Hondori Machi, Neyagawa, Osaka, 572-8551, Japan.
出版信息
Surg Case Rep. 2020 Dec 7;6(1):308. doi: 10.1186/s40792-020-00986-8.
BACKGROUND
Malignant phyllodes tumors (PTs) of the breast occur infrequently and are difficult to treat with adjuvant therapy. Here, we present a case of a female patient with a huge malignant PT with rapid progression in a short period.
CASE PRESENTATION
A 44-year-old woman presented to our hospital with a rapid growth mass in her right breast, measuring 20 cm. She was initially diagnosed as having a borderline phyllodes tumor by core needle biopsy and underwent total mastectomy and artificial dermis was grafted, 20 days later, latissimus dorsi muscle flap and free skin grafting were performed. Two courses of doxorubicin-ifosfamide therapy were administered because of recurrence, but the patient died 4 months after the mastectomy.
CONCLUSIONS
A standard therapeutic strategy for malignant PTs is needed in urgently to reduce the risk of tumor recurrence.
背景
乳腺恶性叶状肿瘤（PTs）发病率低，辅助治疗效果不佳。在此，我们报告1例短期内迅速进展的巨大乳腺恶性PTs女性患者。
病例介绍
一名44岁女性因右乳肿物迅速增大就诊我院，肿物大小20cm。粗针穿刺活检最初诊断为交界性叶状肿瘤，遂行全乳切除术并行人工真皮移植，20天后行背阔肌肌皮瓣游离植皮术。因复发给予两周期阿霉素-异环磷酰胺治疗，但患者在乳房切除术后4个月死亡。
结论
急需制定标准的恶性PTs治疗策略以降低肿瘤复发风险。
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