Cheok Lay Hock, Tang Andy Sing Ong, Desmond Samuel, Wong Yi-Li, Cheong Yaw Kiet, Ng Say Chiew, Cheng Wee Mee, Chua Hock Hin, Teh Cheng Lay
Department of Internal Medicine, Miri Hospital, Sarawak, Ministry of Health, Malaysia.
Department of Radiology, Miri Hospital, Sarawak, Ministry of Health, Malaysia.
IDCases. 2021 Aug 12;26:e01255. doi: 10.1016/j.idcr.2021.e01255. eCollection 2021.
Central nervous system melioidosis is an uncommon presentation of melioidosis infection. We report a case of a disseminated melioidosis infection with central nervous system, pulmonary, spleen, bone and cutaneous involvement in a patient with underlying systemic lupus erythematous. The diagnosis was confirmed based on positive blood and cerebrospinal fluid cultures coupled with radiological findings. Agriculture contact and underlying immunocompromised state were the predisposing risk factors for melioidosis infection in this case. Our patient was successfully treated with 10 weeks of intensive antibiotics therapy and 1 year of eradication antibiotics therapy with significant clinical and radiological improvement.
中枢神经系统类鼻疽是类鼻疽感染的一种罕见表现形式。我们报告一例患有系统性红斑狼疮的患者发生播散性类鼻疽感染，累及中枢神经系统、肺、脾脏、骨骼和皮肤。根据血液和脑脊液培养阳性以及影像学检查结果确诊。农业接触和潜在的免疫功能低下状态是该病例中类鼻疽感染的诱发危险因素。我们的患者通过10周的强化抗生素治疗和1年的根除性抗生素治疗获得成功治愈，临床和影像学均有显著改善。
