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医生知识与老年人群不适当用药之间的关联。

The association between physician knowledge and inappropriate medications for older populations.

作者信息

Vandergrift Jonathan L, Weng Weifeng, Gray Bradley M

机构信息

American Board of Internal Medicine, Philadelphia, Pennsylvania, USA.

出版信息

J Am Geriatr Soc. 2021 Dec;69(12):3584-3594. doi: 10.1111/jgs.17413. Epub 2021 Aug 30.

Abstract

BACKGROUND

Older patients are often prescribed potentially inappropriate medications (PIMs) given their age. We measured the association between a physician's general knowledge and their PIM prescribing.

METHODS

Using a 2013-2017 cross-sectional design, we related a general internist's knowledge (n = 8196) to their prescribing of PIMs to fee-for-service Medicare beneficiaries, age ≥ 66 years with part D coverage, which they saw in the outpatient setting the year after their exam (n = 875,132). Physician knowledge was based on the American Board of Internal Medicine's (ABIM) Internal Medicine Maintenance of Certification (IM-MOC) exam scores. Medications included 72 PIMs from the American Geriatric Society's Beers Criteria and appropriate alternatives to these medications. Logistic regressions controlled for physicians practice/training characteristics and patient-risk factors.

RESULTS

Annually, 11.0% of patients received a PIM and 57.2% received an appropriate alternative medication. Patients seen by physicians scoring in the top versus bottom quartile were 8.6% less likely (95% confidence interval [CI]: -12.7 to -4.5, p < 0.001) to be prescribed a PIM and 4.7% more likely (95% CI: 1.7 to 7.6, p = 0.001) to be prescribed an appropriate alternative medication. The difference in PIM prescribing grew to 12.1% fewer (95% CI: -15.1 to -9.1) patients when limiting the sample to the 58.9% of patients being prescribed a PIM or appropriate alternative medication. Among patients receiving any medication, this was similar to the percent difference in PIM prescribing between solo and large practices (≥50 physicians, -10.2%, 95% CI: 13.6-6.5, p < 0.001) or between group and academic practices (-11.7%, 95% CI: -15.3 to -7.9, p < 0.001). PIM prescribing was more positively associated with patient characteristics including age, gender, and total number of medications prescribed.

CONCLUSIONS

Better physician general knowledge, as measured by an ABIM exam, was associated with fewer PIM prescriptions. Future research should examine whether general educational interventions, such as MOC, effect PIM prescribing.

摘要

背景

老年患者因其年龄因素,常常被开具可能不适当的药物(PIMs)。我们测量了医生的一般知识水平与其开具PIMs之间的关联。

方法

采用2013 - 2017年的横断面设计,我们将普通内科医生的知识水平(n = 8196)与他们为按服务收费的医疗保险受益人(年龄≥66岁且有D部分保险)开具PIMs的情况相关联,这些受益人是他们在考试后次年的门诊中接诊的(n = 875,132)。医生的知识水平基于美国内科医学委员会(ABIM)的内科医学认证维持(IM - MOC)考试成绩。药物包括美国老年医学会Beers标准中的72种PIMs以及这些药物的适当替代药物。逻辑回归分析控制了医生的执业/培训特征和患者风险因素。

结果

每年,11.0%的患者接受了PIMs,57.2%的患者接受了适当的替代药物。由得分处于前四分位数与后四分位数的医生接诊的患者,开具PIMs的可能性降低8.6%(95%置信区间[CI]:-12.7至-4.5,p < 0.001),开具适当替代药物的可能性增加4.7%(95% CI:1.7至7.6,p = 0.001)。当将样本限制为开具PIMs或适当替代药物占比58.9%的患者时,PIMs开具的差异增加到少12.1%(95% CI:-15.1至-9.1)。在接受任何药物治疗的患者中,这与个体诊所和大型诊所(≥50名医生,-10.2%,95% CI:13.6 - 6.5,p < 0.001)或团体诊所和学术诊所之间PIMs开具差异的百分比相似(-11.7%,95% CI:-15.3至-7.9,p < 0.001)。PIMs开具与患者特征(包括年龄、性别和开具药物的总数)的正相关性更强。

结论

通过ABIM考试衡量的医生更好的一般知识水平与更少的PIMs处方相关。未来的研究应考察诸如MOC等一般教育干预措施是否会影响PIMs的开具。

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