Maternité Port-Royal, APHP.Centre-Université de Paris, FHU PREMA, 123 boulevard de Port-Royal, 75014, Paris, France.
Université de Paris, CRESS, Obstetrical Perinatal and Pediatric Epidemiology Research Team, EPOPé, INSERM, INRA, Paris, France.
BMC Pregnancy Childbirth. 2021 Aug 30;21(1):590. doi: 10.1186/s12884-021-04041-8.
To examine disparities by maternal place of birth in the opportunity to make an informed choice about Down syndrome screening, in France, where the national guidelines recommend that physicians offer it to all pregnant women.
We used population-based data from the nationally representative French Perinatal Surveys in 2010 and 2016 (N=24,644 women) to analyze the opportunity for an informed choice for prenatal screening, measured by a composite indicator.
Among the 24 644 women in the study, 20 612 (83.6%) were born in France, 861 (3.5%) elsewhere in Europe, 1550 (6.3%) in North Africa, and 960 (3.9%) in sub-Saharan Africa. The probability of screening was lower for women born outside France. After adjustment for survey year, maternal age, parity, education level, and the maternity unit's level of perinatal care, women born outside France had the opportunity to make an informed choice less often than women born in France. This association remained essentially the same even after excluding women without adequate prenatal care.
Women born outside France, including those with adequate prenatal care, had less opportunity than women born in France to make an informed choice about prenatal screening for Down syndrome.
在法国，国家指南建议医生向所有孕妇提供唐氏综合征筛查，本研究旨在调查产妇出生地差异对唐氏综合征筛查知情选择机会的影响。
我们使用了 2010 年和 2016 年全国代表性法国围产儿调查的基于人群的数据（共 24644 名女性），分析了产前筛查的知情选择机会，通过综合指标进行衡量。
在研究中的 24644 名女性中，20612 名（83.6%）出生在法国，861 名（3.5%）在欧洲其他地区，1550 名（6.3%）在北非，960 名（3.9%）在撒哈拉以南非洲。出生在法国以外的女性筛查概率较低。在调整了调查年份、产妇年龄、产次、教育水平和围产保健单位的围产保健水平后，与出生在法国的女性相比，出生在法国以外的女性进行知情选择的机会较少。即使排除了产前保健不足的女性，这种关联仍然基本相同。
与出生在法国的女性相比，出生在法国以外的女性，包括那些接受了充分产前保健的女性，在唐氏综合征产前筛查方面做出知情选择的机会较少。
