Shin Hyun Bin, Park Hyun Sik, Kim Joo Heon, Park Jinsung
Department of Urology, Eulji University Hospital, Eulji University School of Medicine, Daejeon, Korea.
Department of Pathology, Eulji University Hospital, Eulji University School of Medicine,, Daejeon, Korea.
BMC Urol. 2021 Aug 30;21(1):116. doi: 10.1186/s12894-021-00885-6.
Eosinophilic cystitis is a rare inflammatory disease of the bladder characterized by eosinophilic infiltration of the bladder wall. Most Eosinophilic cystitis cases present with mucosal lesions of the urinary bladder. We present a very rare case of large mass-forming eosinophilic cystitis, involving the inside and outside of the bladder associated with an infected urachal cyst.
A 59-year-old man presented with gross hematuria, fever, dysuria, and suprapubic pain. Computed tomography showed a heterogeneously enhancing mass that measured 7.6 cm × 4 cm located on the anterosuperior portion of the bladder with an internal fluid collection. Cystoscopy revealed a raspberry-like mass lesion on the bladder dome. Transurethral resection of the bladder was initially performed. The mass lesion protruding from inside the bladder was removed, and pus-like fluid was drained. The pathologic diagnosis was eosinophilic cystitis. Follow-up computed tomography showed a remnant mass outside the bladder and urachal cyst. To eliminate the remnant lesion, robot-assisted partial cystectomy was performed. The patient showed no evidence of recurrent disease on follow-up cystoscopy and computed tomography for up to 2 years.
Clinicians should consider the possibility of eosinophilic cystitis in patients who present with hematuria, fever, and suprapubic pain and have both intravesical and extravesical masses.
嗜酸性膀胱炎是一种罕见的膀胱炎症性疾病,其特征为膀胱壁嗜酸性粒细胞浸润。大多数嗜酸性膀胱炎病例表现为膀胱黏膜病变。我们报告一例极为罕见的形成巨大肿块的嗜酸性膀胱炎病例,累及膀胱内外,并伴有感染性脐尿管囊肿。
一名59岁男性患者出现肉眼血尿、发热、排尿困难及耻骨上疼痛。计算机断层扫描显示一个不均匀强化的肿块,大小为7.6厘米×4厘米,位于膀胱前上部,内部有液性聚集。膀胱镜检查发现膀胱顶部有一个覆盆子样肿块病变。最初进行了经尿道膀胱切除术。切除了从膀胱内部突出的肿块病变,并引流了脓性液体。病理诊断为嗜酸性膀胱炎。随访计算机断层扫描显示膀胱外有残余肿块及脐尿管囊肿。为消除残余病变,进行了机器人辅助部分膀胱切除术。在长达2年的随访膀胱镜检查和计算机断层扫描中,患者未显示复发疾病的迹象。
对于出现血尿、发热和耻骨上疼痛且膀胱内和膀胱外均有肿块的患者,临床医生应考虑嗜酸性膀胱炎的可能性。