Department of Urology, First People's Hospital of Zigong City, Zigong, China.
Department of Nephrology, First People's Hospital of Zigong City, Zigong, China.
BMC Urol. 2022 Apr 9;22(1):55. doi: 10.1186/s12894-022-01007-6.
Eosinophilic cystitis (EC) is a rare inflammatory disease characterized by the gathering and infiltration of numerous eosinophilia (EOS) in the bladder wall. Because of Few cases of EC have been reported globally, the epidemiology of EC is not well known. We report herein the details of one very scarce case of large tumor-like eosinophilic cystitis complicated with cystitis glandularis (CG) diagnosed by biopsy.
A 45-year-old Chinese man was referred to our hospital for the treatment of right lumbago and odynuria. Ultrasound examination indicated the low echo on the right portion wall and the neck of the bladder. Computed tomography showed a remarkable enhancing large mass that measured 5.0 cm × 2.3 cm located on the right portion of the bladder with undefined margin. For further treatment, diagnostic transurethral resection of the bladder was performed, the postoperative histopathological diagnosis was EC complicated with CG. After transurethral resection, antibiotics, glucocorticoids, and antihistamines were treated. The patient recovered uneventfully and was discharged on postoperative day 8 without evidence of recurrence followed-up for 6 months.
Large tumor-like eosinophilic cystitis complicated with cystitis glandularis is rare, malignant tumors need to be ruled out. We deem that prompt biopsy led to the exact diagnosis, appropriate treatment led to better prognosis.
嗜酸性膀胱炎（EC）是一种罕见的炎症性疾病，其特征是膀胱壁中大量嗜酸性粒细胞（EOS）聚集和浸润。由于全球报道的 EC 病例很少，因此 EC 的流行病学尚不清楚。我们在此报告一例经活检诊断的非常罕见的大肿瘤样嗜酸性膀胱炎合并腺性膀胱炎（CG）的详细病例。
一名 45 岁的中国男性因右侧腰痛和尿痛被转至我院治疗。超声检查显示膀胱右侧壁和颈部有低回声。计算机断层扫描显示右膀胱部分有一个明显增强的大肿块，大小为 5.0cm×2.3cm，边界不清。为进一步治疗，进行了经尿道膀胱肿瘤切除术，术后组织病理学诊断为 EC 合并 CG。经尿道膀胱肿瘤切除术后，给予抗生素、糖皮质激素和抗组胺药治疗。患者术后恢复顺利，术后 8 天出院，无复发迹象，随访 6 个月。
大肿瘤样嗜酸性膀胱炎合并 CG 罕见，需要排除恶性肿瘤。我们认为及时活检有助于明确诊断，适当治疗有助于改善预后。
