Department of General Surgery, The First Affiliated Hospital of Shantou University Medical College, Shantou, 515041, China.
Diagn Pathol. 2021 Aug 30;16(1):80. doi: 10.1186/s13000-021-01143-x.
Monomorphic epitheliotropic intestinal T-cell lymphomas (MEITL) is a rare and aggressive subtype of lymphoma. The most common site of origin is small intestine. Patients are often presented with diagnosis of intestinal perforation with abdominal pain as the main consulting symptoms. Because of the deficiency of specific diagnostic measures and effective management, diagnosis is often confirmed in advanced stage with poor prognosis.
Here, we introduce a patient who has suffered from abdominal pain and diarrhea, and eventually been diagnosed as Monomorphic epitheliotropic intestinal T-cell lymphomas.
MEITL is rare in clinical practice with deficiency of early diagnostic measures and poor prognosis. Therefore, any patient with ambiguous gastrointestinal symptoms or perforation of the digestive tract where the primary lesion is difficult to identify should be alert to the possibility of this disease.
单纯上皮型肠黏膜 T 细胞淋巴瘤(MEITL)是一种罕见且侵袭性较强的淋巴瘤亚型。最常见的起源部位是小肠。患者常以腹痛为主要就诊症状,表现为肠穿孔而被诊断。由于缺乏特异性诊断措施和有效的治疗管理,诊断往往在晚期才被确认,预后较差。
这里,我们介绍了一位有腹痛和腹泻症状的患者,最终被诊断为单纯上皮型肠黏膜 T 细胞淋巴瘤。
MEITL 在临床上较为罕见,早期诊断措施不足,预后较差。因此,任何有不明原因胃肠道症状或消化道穿孔且原发灶难以确定的患者,都应警惕该病的可能性。