SLU Swedish Biodiversity Centre, Department of Urban and Rural Development, Swedish University of Agricultural Sciences (SLU), 750 07, Uppsala, Sweden.
Department of Animal Environment and Health, SLU, 750 07, Uppsala, Sweden.
BMC Res Notes. 2021 Aug 30;14(1):337. doi: 10.1186/s13104-021-05742-1.
Our aim was to analyse the chromogranin A-derived peptides vasostatin and catestatin in serum from wild boar (Sus scrofa) captured in a corral trap. Acute capture-related stress quickly leads to a release of adrenalin and noradrenalin, but these hormones have a short half-life in blood and are difficult to measure. Chromogranin A (CgA), a glycoprotein which is co-released with noradrenalin and adrenalin, is relatively stable in circulation and the CgA-derived peptides catestatin and vasostatin have been measured in domestic species, but not yet in wildlife.
Vasostatin and catestatin could be measured and the median (range) serum concentrations were 0.91 (0.54-2.86) and 0.65 (0.35-2.62) nmol/L, respectively. We conclude that the CgA-derived peptides vasostatin and catestatin can be measured in wild boar serum and may thus be useful as biomarkers of psychophysical stress.
我们旨在分析圈养陷阱中捕获的野猪(Sus scrofa)血清中的嗜铬粒蛋白 A 衍生肽血管抑肽和卡肽。急性捕获相关的应激会迅速导致肾上腺素和去甲肾上腺素的释放,但这些激素在血液中的半衰期很短,难以测量。嗜铬粒蛋白 A(CgA)是一种与去甲肾上腺素和肾上腺素共同释放的糖蛋白,在循环中相对稳定,已在家畜中测量过 CgA 衍生肽血管抑肽和卡肽,但尚未在野生动物中测量过。
可以测量血管抑肽和卡肽,血清浓度中位数(范围)分别为 0.91(0.54-2.86)和 0.65(0.35-2.62)nmol/L。我们得出结论,CgA 衍生肽血管抑肽和卡肽可以在野猪血清中测量,因此可能是心理生理应激的有用生物标志物。