Neumann F J, Schmid-Schönbein H, Malotta H
Abt. Physiologie, RWTH Aachen, F. R. Germany.
Biorheology. 1987;24(5):463-72. doi: 10.3233/bir-1987-24504.
As the temperature dependence of relative apparent whole blood viscosity eta rel is still controversial, the relation between the temperature dependence of red cell aggregation (RCA) and that of eta rel was examined in normal donors and in patients with venous ulcers of the leg. Apparent whole blood viscosity was measured in the DEER-rheometer (0.01 Pa less than tau less than 2.9 Pa) at 10 degrees C, 20 degrees C, 30 degrees C and 37 degrees C. The instrument was calibrated for each temperature to correct for changes in viscometer geometry. Simultaneously the minimal shear stress tau Tmin to keep RCA dispersed was determined by photometric aggregometry. eta rel was found to increase with decreasing temperature. By basing the relative cold induced increase in eta rel on the state of RCA as defined by the ratio of tau/tau Tmin the relation between both features is verified: With increasing RCA the cold induced increase in eta rel is progressively enhanced.
由于相对表观全血粘度ηrel的温度依赖性仍存在争议，因此在正常献血者和腿部静脉溃疡患者中研究了红细胞聚集（RCA）的温度依赖性与ηrel的温度依赖性之间的关系。在DEER流变仪（0.01 Pa＜τ＜2.9 Pa）中于10℃、20℃、30℃和37℃测量表观全血粘度。针对每个温度对仪器进行校准，以校正粘度计几何形状的变化。同时，通过光度聚集法测定使RCA保持分散的最小剪切应力τTmin。发现ηrel随温度降低而增加。根据τ/τTmin比值定义的RCA状态，将相对冷诱导的ηrel增加作为基础，验证了这两个特征之间的关系：随着RCA增加，冷诱导的ηrel增加逐渐增强。
