Department of Neurology, West Virginia University School of Medicine, Morgantown, WV, USA.
Department of Neurology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Pediatr Dermatol. 2021 Sep;38(5):1298-1301. doi: 10.1111/pde.14789. Epub 2021 Aug 31.
Neurocutaneous melanocytosis (NCM) is characterized by melanocyte deposition in the leptomeninges and brain parenchyma, primarily occurring in children with large or giant congenital melanocytic nevi (LCMN) or multiple congenital melanocytic nevi. Patients with NCM may develop hydrocephalus and increased intracranial pressure, which can be managed with ventriculoperitoneal (VP) shunting. We present the case of a 16-month-old girl who developed peritoneal carcinomatosis and malignant ascites following VP shunting for hydrocephalus secondary to NCM to increase awareness of this rare, but serious, complication of cerebrospinal fluid diversion.
神经皮肤黑色素细胞增多症（NCM）的特征是黑色素细胞在软脑膜和脑实质中的沉积，主要发生在有大或巨大先天性黑色素痣（LCMN）或多发性先天性黑色素痣的儿童中。NCM 患者可能会发生脑积水和颅内压增高，可通过脑室腹膜（VP）分流来治疗。我们报告了一例 16 个月大的女孩，她在因 NCM 导致的脑积水行 VP 分流术后出现腹膜癌转移和恶性腹水，以提高对这种罕见但严重的脑脊液分流并发症的认识。
