Department of Therapeutic Endocrinology, Moscow Regional Research and Clinical Institute (MONIKI), Moscow, Russian Federation.
J Musculoskelet Neuronal Interact. 2021 Sep 1;21(3):364-372.
The aim of this study was to assess the quantitative composition of muscle and adipose tissue in type 2 diabetes mellitus (T2DM) patients on the basis of dual-energy X-ray absorptiometry for the diagnosis of obesity and sarcopenia.
Dual-energy X-ray absorptiometry was administered to 50 patients with T2DM. Evaluation of the composition of muscle and adipose tissue was performed.
The median of Appendicular Lean Mass Index (ALMI) in the general group was 8.04 [7.32; 8.97]. In general, there was a decrease in the appendicular muscle mass with increasing age. According to the results of T-score ALMI and Z-score ALMI, we did not identify patients with sarcopenia. However, the calculation of the T- and Z-criteria, adjusted for fat mass, led to a significant decrease of these parameters and in 98.0% it was possible to identify patients who meet the criteria of sarcopenia.
We did not detect patients with sarcopenia on the basis of ALMI, T-ALMI. After revision of these criteria for fat mass, almost all patients started to meet the criteria of sarcopenia (98.0%).
本研究旨在通过双能 X 射线吸收法（DXA）评估 2 型糖尿病（T2DM）患者的肌肉和脂肪组织的定量组成，以诊断肥胖和肌肉减少症。
对 50 例 T2DM 患者进行 DXA 检查。评估肌肉和脂肪组织的组成。
一般组的四肢瘦体重指数（ALMI）中位数为 8.04[7.32；8.97]。一般来说，随着年龄的增长，四肢肌肉量逐渐减少。根据 ALMI 的 T 评分和 Z 评分结果，我们未发现存在肌肉减少症的患者。然而，对脂肪量进行调整后的 T 和 Z 标准计算，导致这些参数显著下降，98.0%的患者符合肌肉减少症的标准。
我们根据 ALMI、T-ALMI 未检测到存在肌肉减少症的患者。对这些标准进行脂肪量修正后，几乎所有患者都开始符合肌肉减少症的标准（98.0%）。
