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一个中等收入国家心力衰竭注册研究的患者特征和初步结果:波斯心血管疾病/心力衰竭注册研究(PROVE/HF)

Patients Characteristics and Preliminary Outcomes of Heart Failure Registry in A Middle-Income Country: Persian Registry of Cardiovascular Disease/Heart Failure (PROVE/HF).

作者信息

Givi Mahshid, Shafie Davood, Garakyaraghi Mohammad, Yadegarfar Ghasem, Roohafza Hamid Reza, Ahmadi Seyed Abdollah, Nouri Fatemeh, Sarrafzadegan Nizal

机构信息

Heart Failure Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran.

Isfahan Cardiovascular Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran.

出版信息

Galen Med J. 2018 Nov 8;7:e1026. doi: 10.22086/gmj.v0i0.1026. eCollection 2018.

Abstract

BACKGROUND

The Persian Registry of Cardiovascular disease/Heart Failure (PROVE/HF) aimed to studied the demographic, clinical, and diagnostic characteristics and treatment of patients hospitalized for heart failure (HF) and to follow them for short- and long-term outcomes. Its pilot phase started in 2015 in Isfahan aiming to evaluate its feasibility to be scaled up at the national level in later stages. This article describes the method and preliminary results of the first year registry.

MATERIALS AND METHODS

Information of hospitalized patients with preserved and low ejection fraction, were gathered. Patients were followed for 1, 6, and 12 months. During follow-up, information of the patients' current status, medications used during hospitalization, and in case of death, the cause and place were assessed.

RESULT

PROVE/ HF enrolled 787 patients in the first year. The mean age of patients was 70.74 ±12.01 years, and 60.7% of them were men. The most frequent risk factors for the development of HF in the recruited patients was ischemic heart disease (77.9%), and hypertension (63.7%), respectively. The re-admission rate for patients with HF was at least once in 16% and continued until the fifth to ninth re-admission over a one-year period. Among 787 registered patients, 30.9% died in the first year of follow-up, and the in-hospital mortality was 6.2%. The mean hospitalization period was 4.88 days, and 64.2% were hospitalized for >3 days.

CONCLUSION

The annual rate of re-admission and mortality was high, and the use of medication was less than the recommended one inaccordance with the guidelines for the treatment of heart failure.

摘要

背景

波斯心血管疾病/心力衰竭注册研究(PROVE/HF)旨在研究因心力衰竭(HF)住院患者的人口统计学、临床和诊断特征及治疗情况,并对其进行短期和长期随访。其试点阶段于2015年在伊斯法罕启动,旨在评估后期在全国范围内扩大规模的可行性。本文介绍了第一年注册研究的方法和初步结果。

材料与方法

收集了射血分数保留和降低的住院患者信息。对患者进行了1个月、6个月和12个月的随访。在随访期间,评估患者的当前状态、住院期间使用的药物,以及死亡情况下的死因和死亡地点。

结果

PROVE/HF第一年纳入了787例患者。患者的平均年龄为70.74±12.01岁,其中60.7%为男性。招募患者中发生HF的最常见危险因素分别是缺血性心脏病(77.9%)和高血压(63.7%)。HF患者的再入院率在16%至少有一次,并且在一年期间持续到第五至第九次再入院。在787例登记患者中,30.9%在随访的第一年死亡,住院死亡率为6.2%。平均住院时间为4.88天,64.2%的患者住院时间超过3天。

结论

再入院率和死亡率的年发生率较高,并且根据心力衰竭治疗指南,药物使用少于推荐用量。

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本文引用的文献

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Acute heart failure patient profiles, management and in-hospital outcome: results of the Italian Registry on Heart Failure Outcome.
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