Mohtaj Tahereh, Aazami Mathias H, Sazegar Ghassem, Poorzand Hoorak, Hedjazi Aria, Morovatdar Negar, Toorabi Ahmad
Department of Cell Biology and Anatomy, School of Medicine, Medical Sciences University, Mashhad, Iran.
Javad Al-Aemeh Heart Hospital, Honarestan Avenue, Mashhad, Iran.
Galen Med J. 2018 Mar 31;7:e1078. doi: 10.22086/gmj.v0i0.1078. eCollection 2018.
This study aimed to determine the normal dimensions of the mitral annulus (MA) in Iranian population.
This cross-sectional study was conducted using 88 fresh hearts of male and female cadavers for six months in Mashhad, Iran. Normal data were determined by measuring the exact dimensions of the MA in fresh hearts of patients who had died of non-cardiac causes and considering some parameters such as age, gender, stature, and weight. Images of the valves and leaflets were prepared by marking the anterior (A2, midpoint of anterior) and posterior areas of P1, P2, and P3 using a needle. To analyze the data, SPSS version 16 was used.
The means of anatomic area, anatomic perimeter, inter-commissural distance, A2-P1, A2-P2, A2-P3, Base-P1, Base-P2, Base-P3, and Base-A were 14±1.28, 8.3±1, 2.7±0.42, 2.27±0.37, 2.3±0.43, 2.06±0.35, 1.66±0.43, 1.2±0.97, 1.5±0.66, and 3.2±0.52, respectively. Comparison of the age groups regarding valve leaflets showed that Strut-P1 and Base-P2 were significantly different. Comparison of the valve leaflets and sub-valve indicators between the two genders reflected no significant differences. Age groups differed significantly in terms of Strut-P1 and Base-P2 (P=0.004 and P=00.1, respectively).
A2-P3, A2-P1, anatomic perimeter, and anatomic area were found to be related to gender. A2-P1 and A2-P2 and some leaflet indicators such as Strut-P1 and Base-P2 were associated with age, whereas Base-P2 was affected by body mass index.
本研究旨在确定伊朗人群二尖瓣环（MA）的正常尺寸。
本横断面研究在伊朗马什哈德进行，为期6个月，使用了88具男性和女性尸体的新鲜心脏。通过测量死于非心脏原因患者新鲜心脏中MA的精确尺寸，并考虑年龄、性别、身高和体重等参数来确定正常数据。使用针标记P1、P2和P3的前部（A2，前部中点）和后部区域，制备瓣膜和瓣叶的图像。使用SPSS 16版分析数据。
解剖面积、解剖周长、瓣间距离、A2 - P1、A2 - P2、A2 - P3、基部 - P1、基部 - P2、基部 - P3和基部 - A的平均值分别为14±1.28、8.3±1、2.7±0.42、2.27±0.37、2.3±0.43、2.06±0.35、1.66±0.43、1.2±0.97、1.5±0.66和3.2±0.52。各年龄组瓣叶比较显示，支柱 - P1和基部 - P2有显著差异。两性之间瓣叶和瓣下指标比较无显著差异。年龄组在支柱 - P1和基部 - P2方面有显著差异（分别为P = 0.004和P = 00.1）。
发现A2 - P3、A2 - P1、解剖周长和解剖面积与性别有关。A2 - P1和A2 - P2以及一些瓣叶指标如支柱 - P1和基部 - P2与年龄有关，而基部 - P2受体重指数影响。
