Zirna H, Keating S E, DeVincentis A F
Department of Podiatric Surgery, Sheridan Park Hospital, Tonawanda, New York.
J Foot Surg. 1987 Nov-Dec;26(6):496-500.
This article reviews the history of topical bone hemostatic agents, listing advantages and disadvantages of the more commonly used agents. Gelfoam paste and bone wax were chosen to study the effects that bone hemostatic agents have on the occurrence and severity of postoperative edema and pain. The authors discovered 80% of the patients utilizing bone wax, and 91% of the patients receiving Gelfoam paste, had markedly decreased amounts of immediate postoperative edema. Furthermore, 90% of the patients treated with bone wax, and 75% of the patients treated with Gelfoam paste, reported less postoperative pain than anticipated with the surgical procedure performed.
本文回顾了局部骨止血剂的历史，列出了更常用药剂的优缺点。选择明胶海绵糊剂和骨蜡来研究骨止血剂对术后水肿和疼痛的发生及严重程度的影响。作者发现，使用骨蜡的患者中有80%，接受明胶海绵糊剂治疗的患者中有91%，术后立即出现的水肿量明显减少。此外，使用骨蜡治疗的患者中有90%，使用明胶海绵糊剂治疗的患者中有75%，报告的术后疼痛比所进行的手术预期的要少。
