Wilkinson H A, Baker S, Rosenfeld S
J Neurosurg. 1981 May;54(5):664-7. doi: 10.3171/jns.1981.54.5.0664.
The hemostatic properties and effect on osteogenesis of gelatin foam paste and bone wax were compared on surgical bone lesions in experimental animals. Thirty rabbits each received four trephine craniotomies and four lumbar laminectomies. Alternate bone incisions in each animal were treated with either gelatin foam paste or bone wax. Blood loss was measured by absorbing the blood into dry surgical cottonoids weighed before and after use. Bone healing sites of three rabbits were examined histologically to assess the effect of each agent on osteogenesis. The trephination sites of eight rabbits were subjected to fracture force testing at 6 weeks postoperatively to compare the effect ot the two agents on bone healing. No significant difference was found between gelatin foam paste and bone wax in either effectiveness of hemostasis or effect on osteogenesis.
在实验动物的手术骨损伤处，比较了明胶泡沫糊剂和骨蜡的止血特性及对成骨的影响。30只兔子均接受了4次环锯开颅术和4次腰椎椎板切除术。每只动物的交替骨切口分别用明胶泡沫糊剂或骨蜡处理。通过将血液吸收到使用前后称重的干手术棉片中测量失血量。对3只兔子的骨愈合部位进行组织学检查，以评估每种药剂对成骨的影响。对8只兔子的环锯部位在术后6周进行骨折力测试，以比较两种药剂对骨愈合的影响。明胶泡沫糊剂和骨蜡在止血效果或对成骨的影响方面均未发现显著差异。
