患有慢性诱导血容量差异的犬类的心房感受器放电
Atrial receptor discharge in dogs with chronically induced difference in blood volume.
作者信息
Hicks M N, Mary D A, Walters G E
机构信息
Department of Cardiovascular Studies, University of Leeds.
出版信息
J Physiol. 1987 Dec;393:491-7. doi: 10.1113/jphysiol.1987.sp016835.
Abstract
- Urinary responses to stimulation of atrial receptors have been found to be greater in dogs with a high blood volume than in dogs with a low blood volume. Two groups of dogs with different blood volume were examined by distending a large balloon in the left atrium, to stimulate atrial receptors and find out whether the increase in atrial receptor discharge was different in the two groups of dogs. 2. The relationship between atrial receptor discharge and left atrial pressure was determined in twenty-six fibres studied in four dogs with a high blood volume and sixteen fibres studied in three dogs with a low blood volume. 3. The slope of the relationship representing the increase in atrial receptor activity during increases in left atrial pressure, and the activity at each left atrial pressure, were significantly greater in dogs with a high blood volume than in dogs with a low blood volume. 4. This study has shown that the atrial receptor discharge and their responses to increases in left atrial pressure are greater in dogs with a high blood volume than in those with a low blood volume.
摘要
- 已发现，血容量高的犬对心房感受器刺激的泌尿反应比血容量低的犬更强。通过在左心房扩张一个大气球来刺激心房感受器，对两组血容量不同的犬进行检查，以确定两组犬中心房感受器放电的增加是否存在差异。2. 在4只血容量高的犬身上研究了26根纤维，在3只血容量低的犬身上研究了16根纤维，测定了心房感受器放电与左心房压力之间的关系。3. 在左心房压力升高期间，代表心房感受器活动增加的关系斜率以及每个左心房压力下的活动，血容量高的犬比血容量低的犬显著更大。4. 这项研究表明，血容量高的犬的心房感受器放电及其对左心房压力升高的反应比血容量低的犬更大。
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