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树突状肺骨化:八年观察结果。

Dendriform Pulmonary Ossification: Findings from Eight Years of Observation.

机构信息

Department of Thoracic Surgery, JR Tokyo General Hospital, Japan.

出版信息

Intern Med. 2022 Mar 1;61(5):715-717. doi: 10.2169/internalmedicine.7785-21. Epub 2021 Aug 31.

DOI:10.2169/internalmedicine.7785-21
PMID:34471024
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8943377/
Abstract

Dendriform pulmonary ossification is a rare condition characterized by branching bony spicules. A 33-year-old man was clinically considered to have sarcoidosis. At 53 years old, another attending physician performed a detailed evaluation. Computed tomography (CT) showed a fine nodular pattern with foci of calcifications and pulmonary function testing showed peripheral airway obstruction. We performed a surgical biopsy. A histological examination revealed dendriform pulmonary ossification. After surgery, CT showed progression of some lesions; the pulmonary function had also decreased slightly. Since dendriform pulmonary ossification might be a progressive disease, we should perform long-term follow-up.

摘要

树突状肺骨化是一种罕见的疾病,其特征是分支状骨刺。一名 33 岁的男子临床被认为患有结节病。53 岁时,另一位主治医生进行了详细评估。计算机断层扫描(CT)显示细结节模式,有钙化灶,肺功能检查显示周围气道阻塞。我们进行了手术活检。组织学检查显示树突状肺骨化。手术后,CT 显示一些病变进展;肺功能也略有下降。由于树突状肺骨化可能是一种进行性疾病,我们应该进行长期随访。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f35/8943377/b5a7a55eafb3/1349-7235-61-0715-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f35/8943377/f2fe470ef455/1349-7235-61-0715-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f35/8943377/ac220c077a97/1349-7235-61-0715-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f35/8943377/b5a7a55eafb3/1349-7235-61-0715-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f35/8943377/f2fe470ef455/1349-7235-61-0715-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f35/8943377/ac220c077a97/1349-7235-61-0715-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f35/8943377/b5a7a55eafb3/1349-7235-61-0715-g003.jpg

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本文引用的文献

1
Histologically Proven Dendriform Pulmonary Ossification: A Five-case Series.组织学证实的树突状肺骨化:五例系列报告。
Intern Med. 2021 Jul 15;60(14):2261-2268. doi: 10.2169/internalmedicine.5906-20. Epub 2021 Feb 1.
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Progressive Restrictive Ventilatory Impairment in Idiopathic Diffuse Pulmonary Ossification.特发性弥漫性肺骨化中的进行性限制性通气障碍
Intern Med. 2018 Jun 1;57(11):1631-1636. doi: 10.2169/internalmedicine.9433-17. Epub 2018 Jan 11.
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Diffuse Pulmonary Ossification in Fibrosing Interstitial Lung Diseases: Prevalence and Associations.
特发性肺纤维化等肺纤维化性间质性肺疾病中的弥漫性肺实质骨化:患病率及相关因素。
Radiology. 2017 Jul;284(1):255-263. doi: 10.1148/radiol.2017152419. Epub 2017 Feb 9.
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Respiration. 2008;75(3):355-8. doi: 10.1159/000106150. Epub 2007 Jul 18.
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