• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

单家医疗机构手术治疗脑动静脉畸形的疗效:病例系列研究。

The efficacy of surgical treatment of cerebral arteriovenous malformations in a single academic institution: a case series.

机构信息

Kamil Duris, Faculty of Medicine, Masaryk University, 60177 Brno, Czech Republic,

出版信息

Croat Med J. 2021 Aug 31;62(4):353-359. doi: 10.3325/cmj.2021.62.353.

DOI:10.3325/cmj.2021.62.353
PMID:34472738
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8491051/
Abstract

AIM

To report on patients who underwent surgical treatment of arteriovenous malformations (AVMs) at our institution.

METHODS

This retrospective single-center case series enrolled the patients who underwent surgical treatment of pial AVM at the Department of Neurosurgery, University Hospital Brno, between 2005 and 2019. The data are summarized as descriptive statistics presenting basic characteristics in all the patients and in sex or age subgroups.

RESULTS

Fifty patients were enrolled. The majority of AVMs were of Spetzler-Martin grade II (n=27; 54%), localized supratentorialy (n=43; 86%), and half of AVMs were ruptured. A total resection was performed in 48 patients (96%), and a good overall outcome was achieved in 44 patients (88%). Surgery-associated morbidity was 2%, and the mortality rate was 0% due to meticulous selection of patients for surgical treatment.

CONCLUSION

Microsurgery is an appropriate method of treatment for S-M grade I-III pial AVMs. Microsurgery may be used to treat the majority of small-nidus AVMs with a low mortality and morbidity, when precisely planned and performed by an expert vascular team. The meticulous selection of patients for surgical treatment is crucial.

摘要

目的

报告在我们机构接受动静脉畸形(AVM)手术治疗的患者情况。

方法

这是一项回顾性单中心病例系列研究,纳入了 2005 年至 2019 年期间在布尔诺大学医院神经外科接受脑表面 AVM 手术治疗的患者。数据以描述性统计的形式汇总,呈现了所有患者以及按性别或年龄分组的基本特征。

结果

共纳入 50 名患者。大多数 AVM 为 Spetzler-Martin 分级 II 级(n=27;54%),局限于幕上(n=43;86%),一半的 AVM 为破裂型。48 名患者(96%)行完全切除,44 名患者(88%)获得良好的总体预后。手术相关发病率为 2%,死亡率为 0%,这是由于对手术治疗的患者进行了精心选择。

结论

对于 Spetzler-Martin 分级 I-III 级脑表面 AVM,显微手术是一种合适的治疗方法。当由经验丰富的血管团队精心规划和执行时,显微手术可用于治疗大多数小病灶 AVM,其死亡率和发病率较低。对手术治疗的患者进行精心选择至关重要。

相似文献

1
The efficacy of surgical treatment of cerebral arteriovenous malformations in a single academic institution: a case series.单家医疗机构手术治疗脑动静脉畸形的疗效:病例系列研究。
Croat Med J. 2021 Aug 31;62(4):353-359. doi: 10.3325/cmj.2021.62.353.
2
Microsurgery for cerebral arteriovenous malformations: subgroup outcomes in a consecutive series of 288 cases.脑动静脉畸形的显微手术治疗:288 例连续病例的亚组结果。
J Neurosurg. 2017 Apr;126(4):1056-1063. doi: 10.3171/2016.4.JNS153017. Epub 2016 Jun 10.
3
Safety and outcome of combined endovascular and surgical management of low grade cerebral arteriovenous malformations in children compared to surgery alone.比较儿童低级别脑动静脉畸形的血管内联合手术治疗与单纯手术治疗的安全性和结局。
Eur J Radiol. 2019 Jul;116:8-13. doi: 10.1016/j.ejrad.2019.02.016. Epub 2019 Feb 18.
4
Microsurgery for Spetzler-Martin Grade I-III Arteriovenous Malformations: Analysis of Surgical Results and Correlation of Lawton-Young Supplementary Grade and Supplemented Spetzler-Martin Score with Functional Outcome.显微镜手术治疗 Spetzler-Martin 分级 I-III 级动静脉畸形:手术结果分析及 Lawton-Young 补充分级和补充 Spetzler-Martin 评分与功能预后的相关性。
World Neurosurg. 2020 Dec;144:e227-e236. doi: 10.1016/j.wneu.2020.08.101. Epub 2020 Aug 20.
5
A treatment paradigm for high-grade brain arteriovenous malformations: volume-staged radiosurgical downgrading followed by microsurgical resection.一种针对高级别脑动静脉畸形的治疗模式:容积分期放射外科降级治疗后行显微手术切除。
J Neurosurg. 2015 Feb;122(2):419-32. doi: 10.3171/2014.10.JNS1424. Epub 2014 Nov 28.
6
Angiographic follow-up in 37 patients after radiosurgery for cerebral arteriovenous malformations as part of a multimodality treatment approach.作为多模态治疗方法的一部分,对37例接受脑动静脉畸形放射外科治疗后的患者进行血管造影随访。
Stereotact Funct Neurosurg. 1997;69(1-4 Pt 2):136-42. doi: 10.1159/000099865.
7
Spetzler-Martin Grade III arteriovenous malformations: surgical results and a modification of the grading scale.斯佩茨勒-马丁Ⅲ级动静脉畸形:手术结果及分级量表的修订
Neurosurgery. 2003 Apr;52(4):740-8; discussion 748-9. doi: 10.1227/01.neu.0000053220.02268.9c.
8
Onyx Embolization Before the Surgical Treatment of Grade III Spetzler-Martin Brain Arteriovenous Malformations: Single-Center Experience and Technical Nuances.Ⅲ级斯佩茨勒-马丁脑动静脉畸形手术治疗前的Onyx栓塞术:单中心经验及技术细节
World Neurosurg. 2018 Aug;116:e340-e353. doi: 10.1016/j.wneu.2018.04.203. Epub 2018 May 9.
9
Curative treatment for low-grade arteriovenous malformations.低级别动静脉畸形的治疗。
J Neurointerv Surg. 2020 Jan;12(1):48-54. doi: 10.1136/neurintsurg-2019-015115. Epub 2019 Jul 12.
10
Clinical characteristics and surgical results of patients with cerebral arteriovenous malformations.脑动静脉畸形患者的临床特征及手术结果
Surg Neurol. 2005 Feb;63(2):156-61; discussion 161. doi: 10.1016/j.surneu.2004.04.021.

引用本文的文献

1
Enhancing the quality of evidence, comparability, and reproducibility in brain arteriovenous malformations treated with open surgery research: a systematic review and proposal of a reporting guideline for surgical and clinical outcomes.提高脑动静脉畸形开放性手术治疗研究中证据质量、可比性和可重复性:手术和临床结局报告指南的系统评价和建议。
Neurosurg Rev. 2024 Apr 21;47(1):174. doi: 10.1007/s10143-024-02422-z.
2
A Systematic Review Comparing Digital Subtraction Angiogram With Magnetic Resonance Angiogram Studies in Demonstrating the Angioarchitecture of Cerebral Arteriovenous Malformations.一项比较数字减影血管造影与磁共振血管造影在显示脑动静脉畸形血管构筑方面的系统评价
Cureus. 2022 Jun 9;14(6):e25803. doi: 10.7759/cureus.25803. eCollection 2022 Jun.

本文引用的文献

1
Medical management with interventional therapy versus medical management alone for unruptured brain arteriovenous malformations (ARUBA): final follow-up of a multicentre, non-blinded, randomised controlled trial.介入治疗联合药物治疗与单纯药物治疗用于未破裂脑动静脉畸形(ARUBA):一项多中心、非盲、随机对照试验的最终随访
Lancet Neurol. 2020 Jul;19(7):573-581. doi: 10.1016/S1474-4422(20)30181-2.
2
Multimodal cerebral arteriovenous malformation treatment: a 12-year experience and comparison of key outcomes to ARUBA.多模态脑动静脉畸形治疗:12年经验及关键结局与ARUBA研究的比较
J Neurosurg. 2019 Nov 1;133(6):1792-1801. doi: 10.3171/2019.8.JNS19998. Print 2020 Dec 1.
3
Management of Residual Brain Arteriovenous Malformations After Stereotactic Radiosurgery.
立体定向放射治疗后残留脑动静脉畸形的管理
World Neurosurg. 2018 Aug;116:e1105-e1113. doi: 10.1016/j.wneu.2018.05.180. Epub 2018 Jun 1.
4
The Application of the Novel Grading Scale (Lawton-Young Grading System) to Predict the Outcome of Brain Arteriovenous Malformation.新型分级量表(Lawton-Young 分级系统)在预测脑动静脉畸形转归中的应用。
Neurosurgery. 2019 Feb 1;84(2):529-536. doi: 10.1093/neuros/nyy153.
5
Surgical technique and nuances in ruptured versus unruptured arteriovenous malformation surgery.破裂与未破裂动静脉畸形手术的外科技术及细微差别
J Neurosurg Sci. 2018 Aug;62(4):478-483. doi: 10.23736/S0390-5616.18.04413-2. Epub 2018 Mar 26.
6
Critical review of brain AVM surgery, surgical results and natural history in 2017.2017年脑动静脉畸形手术、手术结果及自然史的批判性综述。
Acta Neurochir (Wien). 2017 Aug;159(8):1457-1478. doi: 10.1007/s00701-017-3217-x. Epub 2017 May 29.
7
Brain AVMs: an endovascular, surgical, and radiosurgical update.脑动静脉畸形:血管内治疗、手术治疗及放射外科治疗的最新进展
ScientificWorldJournal. 2014;2014:834931. doi: 10.1155/2014/834931. Epub 2014 Oct 21.
8
Validation of the supplemented Spetzler-Martin grading system for brain arteriovenous malformations in a multicenter cohort of 1009 surgical patients.在1009例手术患者的多中心队列中对补充的脑动静脉畸形Spetzler-Martin分级系统进行验证。
Neurosurgery. 2015 Jan;76(1):25-31; discussion 31-2; quiz 32-3. doi: 10.1227/NEU.0000000000000556.
9
Hemorrhage rates and risk factors in the natural history course of brain arteriovenous malformations.脑动静脉畸形自然病程中的出血率及危险因素
Transl Stroke Res. 2014 Oct;5(5):538-42. doi: 10.1007/s12975-014-0351-0. Epub 2014 Jun 15.
10
Intra-arterial injection of indocyanine green in cerebral arteriovenous malformation surgery.脑动静脉畸形手术中吲哚菁绿的动脉内注射
Turk Neurosurg. 2013;23(5):676-9. doi: 10.5137/1019-5149.JTN.6420-12.0.