脑动静脉畸形自然病程中的出血率及危险因素
Hemorrhage rates and risk factors in the natural history course of brain arteriovenous malformations.
作者信息
Rutledge W Caleb, Ko Nerissa U, Lawton Michael T, Kim Helen
机构信息
Department of Neurological Surgery, University of California, San Francisco, San Francisco, CA, USA.
出版信息
Transl Stroke Res. 2014 Oct;5(5):538-42. doi: 10.1007/s12975-014-0351-0. Epub 2014 Jun 15.
Abstract
Brain arteriovenous malformations (AVMs) are abnormal connections of arteries and veins, resulting in arteriovenous shunting of blood. Primary medical therapy is lacking; treatment options include surgery, radiosurgery, and embolization, often in combination. Judicious selection of AVM patients for treatment requires balancing risk of treatment complications against the risk of hemorrhage in the natural history course. This review focuses on the epidemiology, hemorrhage risk, and factors influencing risk of hemorrhage in the untreated natural course associated with sporadic brain AVM.
摘要
脑动静脉畸形（AVM）是动脉和静脉之间的异常连接，导致血液动静脉分流。目前缺乏主要的药物治疗方法；治疗选择包括手术、放射外科和栓塞，通常联合使用。明智地选择接受治疗的AVM患者需要平衡治疗并发症的风险与自然病程中出血的风险。本综述重点关注散发性脑AVM未经治疗的自然病程中的流行病学、出血风险以及影响出血风险的因素。
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