Polich J
Division of Preclinical Neuroscience and Endocrinology, Research Institute of Scripps Clinic, La Jolla, CA 92037.
Biol Psychol. 1987 Aug;25(1):61-71. doi: 10.1016/0301-0511(87)90067-6.
The P300 component of the event-related brain potential (ERP) was elicited with a simple auditory discrimination task. Subjects were required to respond in three different ways to target stimuli across conditions: (1) silently counting the targets; (2) tapping their index finger every time a target was detected; or (3) pressing a button with their thumb when a target was presented. In addition, ERPs were recorded during each response mode while the subjects' eyes were either open or closed. P300 amplitude was larger for the counting compared to the tapping or button press tasks especially during the eyes closed condition. The peak latency of the P300 was longer when obtained from the counting compared to the tapping and button-press tasks for both eye conditions. Response mode also interacted with electrode site for peak latency. The results suggest that the P300 ERP component is sensitive to the nature of the subject's response during discrimination tasks.
事件相关脑电位（ERP）的P300成分是通过简单的听觉辨别任务诱发的。要求受试者在不同条件下以三种不同方式对目标刺激做出反应：（1）默数目标；（2）每次检测到目标时用食指轻敲；或（3）目标出现时用拇指按按钮。此外，在每种反应模式下记录ERP，同时受试者的眼睛处于睁开或闭合状态。与轻敲或按按钮任务相比，尤其是在闭眼条件下，计数任务的P300波幅更大。在两种眼睛状态下，从计数任务获得的P300的峰值潜伏期比轻敲和按按钮任务更长。反应模式与电极部位在峰值潜伏期方面也存在交互作用。结果表明，P300 ERP成分在辨别任务中对受试者反应的性质敏感。
