Suzuki J, Sakamoto T, Kawakubo K, Hada Y, Amano K, Takenaka K, Hasegawa I, Shiota T, Sugimoto T, Nishikawa J
Second Department of Internal Medicine, Faculty of Medicine, University of Tokyo.
J Cardiol. 1987 Jun;17(2):249-58.
Left ventricular short-axis images were obtained by ECG-gated magnetic resonance imaging (MRI) in nine patients with hypertrophic cardiomyopathy and seven patients with chest pain, all of whom had diagnostic cardiac catheterization including angiography. The accuracy and usefulness of the short-axis image in MRI for measuring wall thickness and dimension and for calculating ejection fraction were evaluated. All patients were examined on an examination couch in the right anterior oblique position in optimal positions to obtain the left ventricular long-axis images in the Z-X plane (conventional coronal plane). Next, the paraxial mode was used to obtain the short-axis images by rotating the Y-Z plane (conventional sagittal plane) around the Y axis. The intervals between the trigger on the middle point of the upstroke of the R wave and the 90 degree pulse of saturation recovery spin echo sequence were 40 msec and 340 msec with a 34 msec echo delay time for the end-diastolic and end-systolic images, respectively. Short-axis images in MRI in end-diastole were utilized to measure wall thickness and dimension in patients with hypertrophic cardiomyopathy and the measurements obtained were compared with those of echocardiography. As for calculating ejection fraction in patients with chest pain, the length of the left ventricular long axis (L) was measured using the MRI long-axis image. The intraventricular sectional area at four levels (S1, S2, S3, S4) were measured using the MRI short-axis image in end-diastole and in end-systole. Left ventricular end-diastolic and end-systolic volumes were calculated using the following formula: V = 1/2 X (L -4.5) X S1 + 1.5 X (S1 + S2 + S3) + 1/3 X 1/2 X (L -4.5) X S4. Ejection fraction by MRI was compared with that by cardiac catheterization (single plane, area-length method). The measurements of wall thickness and dimension by MRI correlated well with those by echocardiography (r = 0.97, p less than 0.01). Ejection fraction calculated by MRI correlated significantly with that by cardiac catheterization (r = 0.82, p less than 0.05). We concluded that the left ventricular short-axis image in MRI is satisfactorily accurate for measuring wall thickness and dimension, and useful for evaluating the left ventricular ejection fraction.
通过心电图门控磁共振成像(MRI)对9例肥厚型心肌病患者和7例胸痛患者进行了左心室短轴图像检查,所有患者均接受了包括血管造影在内的诊断性心导管检查。评估了MRI短轴图像在测量室壁厚度和尺寸以及计算射血分数方面的准确性和实用性。所有患者均在检查床上采取右前斜位的最佳体位,以获取Z-X平面(传统冠状面)的左心室长轴图像。接下来,使用旁轴模式通过围绕Y轴旋转Y-Z平面(传统矢状面)来获取短轴图像。R波上升支中点触发与饱和恢复自旋回波序列90度脉冲之间的间隔,对于舒张末期和收缩末期图像分别为40毫秒和340毫秒,回波延迟时间为34毫秒。利用MRI舒张末期短轴图像测量肥厚型心肌病患者的室壁厚度和尺寸,并将测量结果与超声心动图测量结果进行比较。对于胸痛患者计算射血分数,使用MRI长轴图像测量左心室长轴长度(L)。在舒张末期和收缩末期,使用MRI短轴图像测量四个层面(S1、S2、S3、S4)的心室内截面积。左心室舒张末期和收缩末期容积使用以下公式计算:V = 1/2×(L - 4.5)×S1 + 1.5×(S1 + S2 + S3)+ 1/3×1/2×(L - 4.5)×S4。将MRI测得的射血分数与心导管检查(单平面,面积-长度法)测得的射血分数进行比较。MRI测量的室壁厚度和尺寸与超声心动图测量结果相关性良好(r = 0.97,p < 0.01)。MRI计算的射血分数与心导管检查计算的射血分数显著相关(r = 0.82,p < 0.05)。我们得出结论,MRI中的左心室短轴图像在测量室壁厚度和尺寸方面具有令人满意的准确性,并且对于评估左心室射血分数很有用。