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新冠疫情之后生育会有所不同吗?

Will Procreation Ever Be The Same After COVID-19?

作者信息

Allahbadia Gautam

机构信息

Rotunda-The Center For Human Reproduction, Parel, Mumbai, India.

MMC IVF, Dubai, UAE.

出版信息

J Obstet Gynaecol India. 2021 Aug;71(Suppl 1):1-6. doi: 10.1007/s13224-021-01536-4. Epub 2021 Aug 30.

Abstract

Medically assisted procreation will never be the same again after this China Virus epidemic. With billions of lives being affected by this damaging global pandemic, medically assisted procreation services were not left unharmed with far-reaching consequences. New challenges are now emerging concerning COVID-19, such as associated reproductive implications and the consequences of assisted and natural procreation in the presence of acute SARS-CoV-2 infection and delayed consequences after patient recovery. There is a hypothesis that testicular damage and subsequent infertility may result following COVID-19 infection and the possibility of sexual transmission, as SARS-CoV-2 has been identified in the semen of infected patients. Vaccine hesitancy in young women planning pregnancies has been heightened because of the spread of misinformation on social media stating that COVID-19 vaccines will cause sterility in women. Reassuring data from accidental pregnancies that have occurred in the clinical trials of approved COVID-19 vaccines indicate that vaccination does not harm fertility or increase the rate of miscarriage. Scientists have quickly related to good tissue practices in vitro fertilization and a rethink is on about encouraging biopsies and focusing on safe vitrification protocols keeping in mind that ova, sperm, and embryos could be possible vectors for disease transmission with the limited research on the SARS-CoV-2 virus. Going ahead with segmented IVF without delay, freezing the generated embryos and pushing back the embryo transfer after the pandemic appears to be the best strategy at present. An international group of researchers have proposed a prognostic stratification of more vulnerable infertility cases in order to plan a progressive restart of worldwide fertility treatments.

摘要

在这场“中国病毒”疫情之后,医学辅助生殖将再也不一样了。数十亿人的生命受到这场破坏性的全球大流行的影响,医学辅助生殖服务也未能幸免,产生了深远的后果。现在出现了与新冠病毒相关的新挑战,比如相关的生殖影响以及在急性严重急性呼吸综合征冠状病毒2感染情况下辅助生殖和自然生殖的后果,还有患者康复后的延迟后果。有一种假说认为,感染新冠病毒后可能会导致睾丸损伤及随后的不育,以及性传播的可能性,因为在感染患者的精液中已发现严重急性呼吸综合征冠状病毒2。由于社交媒体上错误信息的传播,称新冠疫苗会导致女性不育,计划怀孕的年轻女性对疫苗的犹豫情绪加剧。已获批新冠疫苗临床试验中意外怀孕的可靠数据表明,接种疫苗不会损害生育能力或增加流产率。科学家们迅速将体外受精与良好的组织操作联系起来,并重新思考鼓励活检以及关注安全的玻璃化方案,因为考虑到对严重急性呼吸综合征冠状病毒2病毒的研究有限,卵子、精子和胚胎可能是疾病传播的载体。立即进行分段体外受精,冷冻产生的胚胎,并在疫情过后推迟胚胎移植,这似乎是目前最好的策略。一组国际研究人员提出了对更易受影响的不育病例进行预后分层,以便规划全球生育治疗的逐步重启。

相似文献

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Will Procreation Ever Be The Same After COVID-19?新冠疫情之后生育会有所不同吗?
J Obstet Gynaecol India. 2021 Aug;71(Suppl 1):1-6. doi: 10.1007/s13224-021-01536-4. Epub 2021 Aug 30.
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SARS-CoV-2 vs. human gametes, embryos and cryopreservation.SARS-CoV-2 与人类配子、胚胎和冷冻保存。
Syst Biol Reprod Med. 2021 Aug;67(4):260-269. doi: 10.1080/19396368.2021.1922537. Epub 2021 Jun 1.

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