Eltemamy Emad, Salama Sameh, Salem Sondos M, Abdel-Rasheed Mazen, Salama Ehab, Elsirgany Sherif, Elnahas Tamer
Obstetrics and Gynecology Department, Faculty of Medicine, Al-Azhar University, Cairo, Egypt.
Reproductive Health and Family Planning Department, National Research Centre, Giza, Egypt.
Middle East Fertil Soc J. 2021;26(1):32. doi: 10.1186/s43043-021-00075-2. Epub 2021 Aug 28.
Many issues need to be studied regarding pregnant women during the SARS-CoV-2 (COVID-19) infection pandemic. The aim of this study was to assess fetal growth, fetal well-being, and any observed gross anomalies that may follow SARS-CoV-2 infection in Egyptian pregnant women. During fetal anomaly scan at 22 weeks, we compared 30 pregnant women with a history of SARS-CoV-2 infection at 6‑12 weeks of gestation (group A) with 60 pregnant women (group B) who had no history of SARS-CoV-2. Then, we followed them on 28 and 34 weeks of gestation with fetal biometry and Doppler study.
Our results revealed no significant difference between both groups regarding fetal biometry, estimated fetal weight, amniotic fluid index, Doppler scan, and gross anomaly scan throughout all visits.
According to the results of our pilot study, SARS-CoV-2 infection in pregnancy was not found to increase the risk of fetal growth restriction or possible fetal gross anomalies. Nevertheless, larger-scale studies are needed to confirm those findings. Perhaps, post-SARS-CoV-2 infection pregnancies may run an uncomplicated course regarding fetal parameters.
在严重急性呼吸综合征冠状病毒2(SARS-CoV-2,即新冠病毒)感染大流行期间,有许多关于孕妇的问题需要研究。本研究的目的是评估埃及孕妇感染SARS-CoV-2后胎儿的生长情况、胎儿健康状况以及观察到的任何明显异常。在孕22周进行胎儿畸形扫描时,我们将30名在妊娠6至12周时有SARS-CoV-2感染史的孕妇(A组)与60名无SARS-CoV-2感染史的孕妇(B组)进行了比较。然后,在孕28周和34周时对她们进行胎儿生物测量和多普勒检查随访。
我们的结果显示,在所有随访中,两组在胎儿生物测量、估计胎儿体重、羊水指数、多普勒扫描和大体畸形扫描方面均无显著差异。
根据我们的初步研究结果,未发现孕期感染SARS-CoV-2会增加胎儿生长受限或可能出现胎儿明显畸形的风险。然而,需要更大规模的研究来证实这些发现。也许,感染SARS-CoV-2后的妊娠在胎儿参数方面可能会顺利进行。