Harenberg Sebastian, St Onge Jennifer, Robinson Jill, Eguakun Omorowa, Feinstein Anthony, Dorsch Kim, Kakar Rumit Singh, Abdulhakim Raghig, Rehman Zia, Shawush Melad, Pillay Vinesh
Int J MS Care. 2021 Jul-Aug;23(4):143-149. doi: 10.7224/1537-2073.2020-007. Epub 2020 Oct 16.
Computerized cognitive training remains an attractive supplemental modality to enhance rehabilitation in multiple sclerosis (MS). The objective of the present study was to assess the usability of three-dimensional multiple-object tracking (3D-MOT) in patients with MS.
In this pilot study, 16 patients with relapsing-remitting MS and nine age-matched controls participated in four 30-minute training sessions of 3D-MOT. Computerized neuropsychological tests, including driving readiness (ie, Useful Field of View) and cognitive function (ie, Stroop Color and Word Test, Paced Visual Serial Addition Test, Symbol Digit Modalities Test) were conducted at baseline and at the conclusion of training.
Although scoring lower in 3D-MOT, the MS group improved their 3D-MOT scores in similar magnitude as the control group. The 3D-MOT training led to significant improvements in driving readiness in the MS group. Taken together, 3D-MOT training showed similar effectiveness in patients with MS as in age-matched controls.
Training with 3D-MOT may be an accessible and remotely administrable supplement to cognitive rehabilitation protocols for patients with MS.
计算机化认知训练仍是增强多发性硬化症（MS）康复效果的一种有吸引力的辅助方式。本研究的目的是评估三维多目标追踪（3D-MOT）在MS患者中的可用性。
在这项初步研究中，16例复发缓解型MS患者和9例年龄匹配的对照者参加了4次每次30分钟的3D-MOT训练课程。在基线和训练结束时进行了计算机化神经心理学测试，包括驾驶准备度（即有用视野）和认知功能（即斯特鲁普颜色和文字测试、视觉连续加法测试、符号数字模式测试）。
尽管MS组在3D-MOT中的得分较低，但该组3D-MOT得分的提高幅度与对照组相似。3D-MOT训练使MS组的驾驶准备度有显著改善。总体而言，3D-MOT训练在MS患者中的效果与年龄匹配的对照者相似。
对于MS患者，3D-MOT训练可能是认知康复方案中一种可及且可远程实施的补充方式。
