Te Dorsthorst Manon, van Balken Michael, Janssen Dick, Heesakkers John, Martens Frank
Radboudumc, Geert Grooteplein Zuid 10, Nijmegen, 6500 HB, Netherlands.
Rijnstate, Arnhem, Gelderland, Netherlands.
Ther Adv Urol. 2021 Aug 31;13:17562872211041470. doi: 10.1177/17562872211041470. eCollection 2021 Jan-Dec.
Overactive bladder syndrome (OAB) is defined as urinary urgency, with or without urgent urinary incontinence; it is often associated with urinary frequency and nocturia, in the absence of any pathological or metabolic conditions that may cause or mimic OAB. The aim of this study was to evaluate the long-term real-life adherence of transcutaneous tibial nerve stimulation (TTNS) in the treatment of OAB, patient satisfaction of the treatment, and reasons for quitting therapy.
In this single center study, all patients who had a positive effect on percutaneous tibial nerve stimulation (PTNS) and continued to receive home-based treatment with TTNS since 2012 were included for analysis. Patients were retrospectively asked to fill out a questionnaire regarding satisfaction, reasons for quitting, and additional or next line of therapy.
We included 42 patients for this study, 81% of these patients were female ( = 34). The median age was 67 years (range 36-86). Most of the patients (64%, = 27) were diagnosed with OAB wet. The median TTNS treatment persistence was 16 months (range 1-112 months). Reasons and percentages for stopping therapy were: 55% stopped treatment due to loss of effect, and 24% stopped because of preferring other type of neuromodulation. The mean satisfaction score (scale 1-10) in patients who continued TTNS was 6.2 ( = 9, SD 1.30) 5.4 ( = 29, SD 2.24) for patients who quit therapy. We did not find a statistically significant difference between the two groups ( = 0.174).
TTNS, although effective in the short-term, is not effective in the long-term. In combination with a low satisfaction rate among patients, there is a need for improvement in terms of OAB treatment modalities.
膀胱过度活动症(OAB)的定义为尿急,伴有或不伴有急迫性尿失禁;常伴有尿频和夜尿,且不存在任何可能导致或模拟OAB的病理或代谢状况。本研究的目的是评估经皮胫神经刺激(TTNS)治疗OAB的长期实际依从性、患者对治疗的满意度以及停止治疗的原因。
在这项单中心研究中,纳入了自2012年以来对经皮胫神经刺激(PTNS)有积极反应并继续接受TTNS家庭治疗的所有患者进行分析。回顾性地要求患者填写一份关于满意度、停止治疗原因以及额外或下一步治疗的问卷。
本研究纳入了42例患者,其中81%(n = 34)为女性。中位年龄为67岁(范围36 - 86岁)。大多数患者(64%,n = 27)被诊断为伴尿失禁的OAB。TTNS治疗的中位持续时间为16个月(范围1 - 112个月)。停止治疗的原因及百分比为:55%因疗效丧失而停止治疗,24%因更喜欢其他类型的神经调节而停止治疗。继续接受TTNS治疗的患者的平均满意度评分(1 - 10分制)为6.2(n = 9,标准差1.30),停止治疗的患者为5.4(n = 29,标准差2.24)。我们未发现两组之间存在统计学显著差异(P = 0.174)。
TTNS虽然在短期内有效,但长期无效。结合患者满意度较低的情况,OAB治疗方式需要改进。