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针对副交感神经活动以改善自主神经张力和临床结果。

Targeting Parasympathetic Activity to Improve Autonomic Tone and Clinical Outcomes.

机构信息

Department of Biomedical Engineering, George Washington University, Washington, District of Columbia.

Division of Pulmonary Medicine, Department of Medicine, George Washington University, Washington, District of Columbia.

出版信息

Physiology (Bethesda). 2022 Jan 1;37(1):39-45. doi: 10.1152/physiol.00023.2021. Epub 2021 Sep 6.

Abstract

In this review we will briefly summarize the evidence that autonomic imbalance, more specifically reduced parasympathetic activity to the heart, generates and/or maintains many cardiorespiratory diseases and will discuss mechanisms and sites, from myocytes to the brain, that are potential translational targets for restoring parasympathetic activity and improving cardiorespiratory health.

摘要

在这篇综述中,我们将简要总结自主神经失衡(更具体地说是心脏副交感活动减少)产生和/或维持许多心肺疾病的证据,并讨论从心肌到大脑的潜在机制和靶点,这些靶点可能成为恢复副交感活动和改善心肺健康的治疗靶点。

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