代谢组学可以为围产期营养提供新的见解。
Metabolomics can provide new insights into perinatal nutrition.
机构信息
Neonatal Intensive Care Unit, AOU Cagliari Department of Surgery, University of Cagliari, Cagliari, Italy.
出版信息
Acta Paediatr. 2023 Feb;112(2):233-241. doi: 10.1111/apa.16096. Epub 2021 Sep 13.
Abstract
Perinatal nutrition is a key factor related to the Developmental Origin of Health and Disease hypothesis, which states that each and every event that happens during the periconceptional period and pregnancy can affect the health status of an individual. Metabolomics can be a very useful tool for gathering information about the effect of perinatal nutrition on both mothers and newborn infants. This non-systematic review focuses on the main metabolites detected by this technique, with regard to gestational diabetes, intrauterine growth restriction and breast milk. Conclusion. Nutrition, metabolome and microbiome interactions are gaining interest in the scientific community.
摘要
围产期营养是与健康和疾病的发育起源假说相关的关键因素，该假说指出，围孕期和怀孕期间发生的每一个事件都可能影响个体的健康状况。代谢组学可以是一个非常有用的工具，用于收集关于围产期营养对母亲和新生儿影响的信息。本非系统性综述重点介绍了该技术检测到的主要代谢物，涉及妊娠期糖尿病、宫内生长受限和母乳。结论：营养、代谢组学和微生物组的相互作用正在引起科学界的兴趣。
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