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加速球囊逆行经静脉闭塞术(BRTO):对抗孤立性胃静脉曲张(IGV)的有效武器。

Accelerated balloon-retrograde transvenous obliteration (BRTO): an effective tool in the Arsenal against isolated gastric varices (IGV).

机构信息

Internal Medicine, Hurley Medical Center, Flint, Michigan, USA.

Division of Gastroenterology & Hepatology, Department of Internal Medicine, Louisiana State University Health Sciences Center, Shreveport, Louisiana, USA.

出版信息

BMJ Case Rep. 2021 Sep 6;14(9):e244405. doi: 10.1136/bcr-2021-244405.

DOI:10.1136/bcr-2021-244405
PMID:34489255
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8422294/
Abstract

Gastric and oesophageal variceal bleeding poses high morbidity and mortality in cirrhosis. Amongst all types, isolated gastric varices (IGV) carry the highest propensity to bleed. Successful outcomes combine endoscopic and interventional radiology approaches using ligation, coils, glue or sclerosants. Transjugular intrahepatic portosystemic shunt success is only seen in a subset of patients, while balloon-retrograde transvenous obliteration (BRTO) has demonstrated high efficacy in preventing rebleeding and morbidity in patients with a myriad of anatomies and shunts. The American Association for the Study of Liver disease guidelines do not favour any particular modality; however, recent trials and meta-analyses support BRTO as the first-line therapy. Despite promising results, BRTO adoption is limited by procedural time, patient length-of-stay and equipment compatibilities hindering scalability in academic and community settings. To address these concerns, we present a successfully treated case of IGV with a revised technique called accelerated BRTO.

摘要

胃食管静脉曲张出血在肝硬化患者中具有较高的发病率和死亡率。在所有类型中,孤立性胃静脉曲张(IGV)出血的风险最高。成功的治疗需要结合内镜和介入放射学方法,包括结扎、线圈、胶或硬化剂。经颈静脉肝内门体分流术(TIPS)仅适用于一部分患者,而球囊逆行静脉闭塞术(BRTO)在预防各种解剖和分流患者再出血和并发症方面显示出了很高的疗效。美国肝病研究协会指南并不支持任何特定的治疗方法;然而,最近的试验和荟萃分析支持 BRTO 作为一线治疗。尽管结果令人鼓舞,但 BRTO 的应用受到操作时间、患者住院时间和设备兼容性的限制,在学术和社区环境中的可扩展性受到阻碍。为了解决这些问题,我们提出了一个成功治疗孤立性胃静脉曲张的病例,采用了一种称为加速 BRTO 的改良技术。

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本文引用的文献

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Endoscopic Cyanoacrylate Injection Versus Balloon-Occluded Retrograde Transvenous Obliteration for Prevention of Gastric Variceal Bleeding: A Randomized Controlled Trial.内镜氰基丙烯酸酯注射与球囊闭塞逆行经静脉断流术预防胃静脉曲张出血的随机对照试验。
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Trends in the Burden of Chronic Liver Disease Among Hospitalized US Adults.美国住院成年人群慢性肝脏疾病负担的变化趋势。
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Comparison of the Effects of TIPS versus BRTO on Bleeding Gastric Varices: A Meta-Analysis.经颈静脉肝内门体分流术(TIPS)与 BRTO 治疗胃静脉曲张出血的效果比较:一项荟萃分析。
Can J Gastroenterol Hepatol. 2020 Feb 11;2020:5143013. doi: 10.1155/2020/5143013. eCollection 2020.
4
Balloon-Occluded Retrograde Transvenous Obliteration (BRTO) Versus Transjugular Intrahepatic Portosystemic Shunt (TIPS) for Treatment of Gastric Varices Because of Portal Hypertension: A Systematic Review and Meta-Analysis.球囊闭塞逆行经静脉闭塞术(BRTO)与经颈静脉肝内门体分流术(TIPS)治疗门静脉高压性胃静脉曲张:系统评价和荟萃分析。
J Clin Gastroenterol. 2020 Aug;54(7):655-660. doi: 10.1097/MCG.0000000000001275.
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An Unusual Presentation of Gastric Variceal Hemorrhage.胃静脉曲张出血的一种不寻常表现
Cureus. 2019 Aug 16;11(8):e5406. doi: 10.7759/cureus.5406.
6
Endoscopic Ultrasound-Guided Coil Injection Therapy for Gastric Variceal Bleeding Not Amenable to Interventional Radiology-Guided Therapies.内镜超声引导下线圈注射治疗对介入放射学引导治疗无效的胃静脉曲张出血
ACG Case Rep J. 2019 Feb 13;6(1):e00013. doi: 10.14309/crj.0000000000000013. eCollection 2019 Jan.
7
Current Approaches to the Treatment of Gastric Varices: Glue, Coil Application, TIPS, and BRTO.当前治疗胃静脉曲张的方法:胶、线圈应用、TIPS 和 BRTO。
Medicina (Kaunas). 2019 Jul 3;55(7):335. doi: 10.3390/medicina55070335.
8
Update on management of gastric varices.胃静脉曲张管理的最新进展。
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J Vasc Interv Radiol. 2018 Sep;29(9):1325-1327. doi: 10.1016/j.jvir.2018.02.010.