Center for Stem Cell and Regenerative Medicine, Tokyo Medical and Dental University (TMDU), 1-5-45 Yushima, Bunkyo-ku, Tokyo, Japan.
Kanagawa Institute of Industrial Science and Technology, 3-2-1 Sakado, Takatsu-Ku, Kawasaki, Kanagawa, Japan.
Eur Radiol. 2022 Mar;32(3):1429-1437. doi: 10.1007/s00330-021-08253-6. Epub 2021 Sep 7.
Radiographs are the most widespread imaging tool for diagnosing osteoarthritis (OA) of the knee. Our purpose was to determine which of the two factors, medial meniscus extrusion (MME) or cartilage thickness, had a greater effect on the difference in the minimum joint space width (mJSW) at the medial compartment between the extension anteroposterior view (extension view) and the 45° flexion posteroanterior view (Rosenberg view).
The subjects were 546 participants (more than 50 females and 50 males in their 30 s, 40 s, 50 s, 60 s, and 70 s) in the Kanagawa Knee Study. The mJSW at the medial compartment was measured from both the extension and the Rosenberg views, and the "mJSW difference" was defined as the mJSW in the Rosenberg view subtracted from the mJSW in the extension view. The cartilage region was automatically extracted from MRI data and constructed in three dimensions. The medial region of the femorotibial joint cartilage was divided into 18 subregions, and the cartilage thickness in each subregion was determined. The MME was also measured from MRI data.
The mJSW difference and cartilage thickness were significantly correlated at 4 subregions, with 0.248 as the highest absolute value of the correlation coefficient. The mJSW difference and MME were also significantly correlated, with a significantly higher correlation coefficient (0.547) than for the mJSW difference and cartilage thickness.
The MME had a greater effect than cartilage thickness on the difference between the mJSW at the medial compartment in the extension view and in the Rosenberg view.
• The difference in the width at the medial compartment of the knee between the extension and the flexion radiographic views was more affected by medial meniscus extrusion than by cartilage thickness.
X 线片是诊断膝关节骨关节炎(OA)最广泛使用的影像学工具。我们的目的是确定内侧半月板突出(MME)或软骨厚度这两个因素中,哪一个对伸展前后位(伸展位)和 45°屈曲前后位(Rosenberg 位)之间内侧间室最小关节间隙宽度(mJSW)差值的影响更大。
本研究纳入了 546 名参与者(30 多岁、40 多岁、50 多岁、60 多岁和 70 多岁的女性和男性均多于 50 名),这些参与者来自神奈川膝关节研究。从伸展位和 Rosenberg 位测量内侧间室的 mJSW,定义 mJSW 差值为 Rosenberg 位 mJSW 减去伸展位 mJSW。从 MRI 数据中自动提取软骨区域并构建三维模型。将股骨胫骨关节软骨的内侧区域分为 18 个亚区,并确定每个亚区的软骨厚度。还从 MRI 数据中测量 MME。
mJSW 差值与 4 个亚区的软骨厚度显著相关,相关系数绝对值最高为 0.248。mJSW 差值与 MME 也显著相关,相关系数(0.547)显著高于 mJSW 差值与软骨厚度的相关系数。
MME 对伸展位和 Rosenberg 位之间内侧间室 mJSW 差值的影响大于软骨厚度。
• 膝关节伸展位和屈曲位 X 线片上内侧间室宽度的差异受内侧半月板突出的影响大于软骨厚度。