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通过使用MRI的三维分析发现，内侧半月板覆盖率与15个内侧间室亚区域的膝关节软骨厚度之间的关联。

The association of the medial meniscus covering ratio with knee cartilage thickness at 15 medial compartment subregions as found by three-dimensional analysis using MRI.

作者信息

Ozeki Nobutake, Koga Hideyuki, Nakamura Tomomasa, Katagiri Hiroki, Nakagawa Yusuke, Hoshino Takashi, Katakura Mai, Amemiya Masaki, Yoshihara Aritoshi, Katano Hisako, Mizuno Mitsuru, Endo Kentaro, Masumoto Jun, Sekiya Ichiro

机构信息

Center for Stem Cell and Regenerative Medicine Tokyo Medical and Dental University Tokyo Japan.

Department of Joint Surgery and Sports Medicine, Graduate School of Medical and Dental Sciences Tokyo Medical and Dental University Tokyo Japan.

出版信息

J Exp Orthop. 2024 Aug 27;11(3):e70005. doi: 10.1002/jeo2.70005. eCollection 2024 Jul.

DOI:10.1002/jeo2.70005
PMID:39193488
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11347932/
Abstract

PURPOSE

The correlation of cartilage thickness measured by three-dimensional (3D) magnetic resonance imaging (MRI) and the medial meniscal coverage ratio (MMCR), which presented pathology of the medial meniscus extrusion (MME) in 3D MRI, has not yet been elucidated. The study's purpose was to retrospectively verify whether the average cartilage thickness calculated by the automatic MRI 3D analysis system for each subregion was correlated with MMCR.

METHODS

A total of 60 patients underwent medial meniscus repair or high tibial osteotomy to treat their medial knee osteoarthritis. Cartilage thickness and MMCR were automatically calculated using 3D MRI software. The MMCR was defined as the ratio of the area covered by the meniscus within the medial tibial cartilage area to the total medial tibial cartilage area. The association between MMCR and the average cartilage thickness at 15 subregions in the medial femoral condyle (MFC) and medial tibial plateau (MTP) was evaluated using Spearman's rank correlation coefficient.

RESULTS

Kellgren-Lawrence grade exhibited a negative correlation with MMCR and a positive correlation with MME width. Cartilage thickness in the MTP had a moderately positive correlation with MMCR at four subregions and a weakly positive correlation at another subregion. Cartilage thickness in the MFC showed a moderately positive correlation with MMCR at five subregions and a weakly positive correlation at one subregion.

CONCLUSIONS

Cartilage thickness calculated by automatic MRI 3D analysis system had a positive correlation with MMCR for all subregions of the anterior and middle subregions in the MFC and for five regions of nine subregions of the anterior and middle subregions in the MTP.

LEVEL OF EVIDENCE

Level II, cross-sectional study (diagnosis).

摘要

目的

三维（3D）磁共振成像（MRI）测量的软骨厚度与内侧半月板覆盖比（MMCR）之间的相关性尚未阐明，而MMCR在3D MRI中提示内侧半月板挤出（MME）的病理情况。本研究的目的是回顾性验证自动MRI 3D分析系统计算的每个子区域的平均软骨厚度是否与MMCR相关。

方法

共有60例患者接受内侧半月板修复或高位胫骨截骨术以治疗其内侧膝关节骨关节炎。使用3D MRI软件自动计算软骨厚度和MMCR。MMCR定义为内侧胫骨软骨区域内半月板覆盖面积与内侧胫骨软骨总面积之比。使用Spearman等级相关系数评估MMCR与股骨内侧髁（MFC）和胫骨内侧平台（MTP）15个子区域的平均软骨厚度之间的关联。

结果

Kellgren-Lawrence分级与MMCR呈负相关，与MME宽度呈正相关。MTP中的软骨厚度在四个子区域与MMCR呈中度正相关，在另一个子区域呈弱正相关。MFC中的软骨厚度在五个子区域与MMCR呈中度正相关，在一个子区域呈弱正相关。

结论

自动MRI 3D分析系统计算的软骨厚度与MFC前中部所有子区域以及MTP前中部九个子区域中的五个区域的MMCR呈正相关。

证据水平

II级，横断面研究（诊断）。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d921/11347932/b8defd3e0b61/JEO2-11-e70005-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d921/11347932/d30b90b7db59/JEO2-11-e70005-g007.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d921/11347932/806d9c228dd0/JEO2-11-e70005-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d921/11347932/4d1e4c9b834f/JEO2-11-e70005-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d921/11347932/e02e89458c33/JEO2-11-e70005-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d921/11347932/b8defd3e0b61/JEO2-11-e70005-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d921/11347932/d30b90b7db59/JEO2-11-e70005-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d921/11347932/3c9c207896a8/JEO2-11-e70005-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d921/11347932/eb57bad0ae09/JEO2-11-e70005-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d921/11347932/806d9c228dd0/JEO2-11-e70005-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d921/11347932/4d1e4c9b834f/JEO2-11-e70005-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d921/11347932/e02e89458c33/JEO2-11-e70005-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d921/11347932/b8defd3e0b61/JEO2-11-e70005-g005.jpg

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Association between knee cartilage thickness determined by magnetic resonance imaging three-dimensional analysis and the International Cartilage Repair Society (ICRS) arthroscopic grade.膝关节磁共振三维分析测定的软骨厚度与国际软骨修复学会（ICRS）关节镜分级的相关性。
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The relationship between meniscal pathologies, cartilage loss, joint replacement and pain in knee osteoarthritis: a systematic review.
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