Department of Physical Therapy, Niigata University of Health and Welfare, 1398 Shimami-cho, Kita-ku, Niigata, 950-3198, Japan.
Department of Geriatric Medicine, Hospital, National Center for Geriatrics and Gerontology, 7-430 Morioka, Obu, Aichi, 474-8511, Japan.
Aging Clin Exp Res. 2022 Mar;34(3):535-543. doi: 10.1007/s40520-021-01968-y. Epub 2021 Sep 7.
Osteosarcopenia is a newly described, aging-associated condition. Social frailty is an important condition whose prevalence may have risen by physical distancing during the coronavirus disease 2019 pandemic. However, the relationship between these two remains unclear.
To examine the association between osteosarcopenia and social frailty.
This cross-sectional study was conducted using data from outpatients visiting general geriatric hospital frailty clinics. Bone mineral density (BMD) and muscle mass were measured using dual X-ray absorptiometry. Osteoporosis was defined as a BMD of < 70% of the young adult mean, according to the Japan Osteoporosis Society. Sarcopenia was diagnosed as per the Asian Working Group for Sarcopenia 2019 recommendation. Osteosarcopenia was defined as the co-existence of osteoporosis and sarcopenia. We defined social frailty using a questionnaire comprising four items: general resources, social resources, social behavior, and basic social needs. Ordinal logistic regression analysis was performed with social frailty status and osteosarcopenia as the dependent and independent variables, respectively.
We included 495 patients (mean age = 76.5 ± 7.2 years) in the analysis; of these, 58.2% were robust and 17.2%, 13.5%, and 11.1% had osteoporosis alone, sarcopenia alone, and osteosarcopenia, respectively. Social frailty prevalence increased stepwise from 8.0% in robust patients to 11.8%, 17.9%, and 29.1% among those with osteoporosis alone, sarcopenia alone, and osteosarcopenia, respectively (P < 0.001). Logistic regression analysis revealed that only osteosarcopenia was significantly associated with social frailty (pooled odds ratio: 2.117; 95% confidence interval: 1.104-4.213).
Comprehensive assessment of osteosarcopenia and social frailty is needed for disability prevention in older adults.
骨肌减少症是一种新描述的与衰老相关的疾病。社会脆弱性是一种重要的疾病，其患病率可能因 2019 年冠状病毒病大流行期间的身体疏远而上升。然而，这两者之间的关系尚不清楚。
研究骨肌减少症与社会脆弱性之间的关系。
本横断面研究使用来自普通老年医院虚弱诊所就诊的门诊患者的数据进行。使用双能 X 射线吸收法测量骨矿物质密度（BMD）和肌肉质量。骨质疏松症根据日本骨质疏松症学会的定义为 BMD 低于年轻成人平均值的 70%。肌少症按照亚洲肌少症工作组 2019 年的建议进行诊断。骨肌减少症定义为骨质疏松症和肌少症并存。我们使用包含四项内容的问卷来定义社会脆弱性：一般资源、社会资源、社会行为和基本社会需求。将社会脆弱性状态和骨肌减少症作为因变量和自变量，进行有序逻辑回归分析。
我们分析了 495 名患者（平均年龄 76.5 ± 7.2 岁）；其中，58.2%为健壮者，17.2%、13.5%和 11.1%分别为单纯骨质疏松症、单纯肌少症和骨肌减少症患者。社会脆弱性的患病率从健壮患者的 8.0%逐渐增加到单纯骨质疏松症、单纯肌少症和骨肌减少症患者的 11.8%、17.9%和 29.1%（P < 0.001）。逻辑回归分析显示，只有骨肌减少症与社会脆弱性显著相关（合并优势比：2.117；95%置信区间：1.104-4.213）。
需要对骨肌减少症和社会脆弱性进行综合评估，以预防老年人的残疾。
