Lv Shan-Guang, Liu Hao, Du Jia, Ruan Chen, Zhang Wei-Bo, Feng Pei-Pei, Zhang Yan-Yan
Department of Acupuncture and Moxibustion, Zhejiang Provincial Tongde Hospital, Hangzhou 310012, China.
Zhongguo Zhen Jiu. 2021 Sep 12;41(9):999-1002. doi: 10.13703/j.0255-2930.20200721-k0008.
To explore the therapeutic effect on rheumatoid arthritis treated with 's abdominal acupuncture for "guiding to the source" plus "opening four gates on the abdomen" and the relevant effect mechanism.
A total of 104 patients with rheumatoid arthritis were randomized into and an observation group (52 cases, 1 case dropped off) and a control group (52 cases, 3 cases dropped off). In the control group, methotrexate tablets were prescribed for oral administration, 5 mg each time, once a week. In the observation group, on the base of the treatment as the control group, 's abdominal acupuncture was combined. The acupoints included Zhongwan (CV 12), Xiawan (CV 10), Guanyuan (CV 4), Qihai (CV 6), Huaroumen (ST 24), Wailing (ST 26), etc. The treatment was given once every two days, 3 times weekly. Totally 12 weeks were required in the two groups. Before and after treatment, the score of TCM symptoms (including joint pain, the range of motion, joint swelling and morning stiffness), and the levels of erythrocyte sedimentation rate (ESR), rheumatoid factor (RF) and C-reactive protein (CRP) were observed and the clinical therapeutic effect was assessed in the two groups.
After treatment, the total effective rate was 88.2% (45/51) in the observation group, higher than 73.5% (36/49) in the control group (<0.05). The score of each TCM symptom and the total scores after treatment were all lower than those before treatment in the two groups (<0.05), and these scores in the observation group were lower than the control group (<0.05). After treatment, the levels of ESR, RF and CRP were all lower than those before treatment in the two groups (<0.05), while the levels of those indexes in the observation group were lower than the control group (<0.05).
's abdominal acupuncture for "guiding to the source" plus "opening four gates on the abdomen" as the adjunctive therapy effectively relieves the clinical symptoms in the patients with rheumatoid arthritis, which is related to the reduction of ESR, RF and CRP in mechanism.
探讨腹针“引气归元”加“腹部四关”治疗类风湿关节炎的疗效及相关作用机制。
将104例类风湿关节炎患者随机分为观察组(52例,脱落1例)和对照组(52例,脱落3例)。对照组予甲氨蝶呤片口服,每次5mg,每周1次。观察组在对照组治疗基础上联合腹针治疗。穴位包括中脘(CV12)、下脘(CV10)、关元(CV4)、气海(CV6)、滑肉门(ST24)、外陵(ST26)等。治疗每两天1次,每周3次。两组均治疗12周。观察两组治疗前后中医症状积分(包括关节疼痛、活动度、关节肿胀及晨僵)、红细胞沉降率(ESR)、类风湿因子(RF)及C反应蛋白(CRP)水平,并评价临床疗效。
治疗后,观察组总有效率为88.2%(45/51),高于对照组的73.5%(36/49)(P<0.05)。两组治疗后各中医症状积分及总分均低于治疗前(P<0.05),且观察组低于对照组(P<0.05)。治疗后,两组ESR、RF及CRP水平均低于治疗前(P<0.05),且观察组上述指标低于对照组(P<0.05)。
腹针“引气归元”加“腹部四关”作为辅助治疗可有效缓解类风湿关节炎患者的临床症状,其机制与降低ESR、RF及CRP有关。