Human Neurosciences Department, Sapienza University, Rome, Italy.
Santa Maria Goretti Hospital, Latina, Italy.
World Neurosurg. 2021 Dec;156:e57-e63. doi: 10.1016/j.wneu.2021.08.127. Epub 2021 Sep 4.
Minimally invasive transforaminal lumbar interbody fusion (MIS-TLIF) is one of several approaches to lumbar interbody fusion that has proven to be a safe and effective treatment for symptomatic lumbar degenerative disease The clinical outcomes of MIS-TLIF are generally favorable, but there is still controversy regarding its ability to restore sagittal alignment. For this reason, expandable transforaminal lumbar interbody fusion cages have been developed and designed to improve ability to restore disc height and segmental lordosis. The use of expandable cages in transforaminal lumbar interbody fusion has increased drastically; however, it is not clear how effective cage expansion is in regard to disc space lordosis, distraction, and long-term outcome.
We reviewed a cohort of patients with symptomatic lumbar degenerative disc pathology who underwent MIS-TLIF at our institution. We compared clinical and radiographic outcomes of expandable versus nonexpandable cage use in MIS-TLIF focusing on mean changes in segmental lordosis, disc height, and postoperative complications. The results were compared with other studies reported in the international literature.
Mean change in segmental lordosis was not significantly different between the 2 groups. A significantly higher rate of postoperative subsidence was demonstrated in the expandable cage group.
This study established that expandable cage use in single-level transforaminal lumbar interbody fusion did not reduce the rate of postoperative complications, but rather significantly increased a patient's risk of postoperative subsidence. Expandable cages do not presently demonstrate improved clinical outcomes or improved sagittal alignment compared with static cages.
微创经椎间孔腰椎体间融合术(MIS-TLIF)是几种腰椎体间融合术之一,已被证明是治疗有症状的腰椎退行性疾病的一种安全有效的方法。MIS-TLIF 的临床效果通常是良好的,但关于其恢复矢状面排列的能力仍存在争议。出于这个原因,开发并设计了可扩张经椎间孔腰椎体间融合 cage,以提高恢复椎间盘高度和节段前凸的能力。可扩张 cage 在经椎间孔腰椎体间融合中的应用急剧增加;然而,尚不清楚 cage 扩张在椎间盘空间前凸、撑开和长期结果方面的效果如何。
我们回顾了在我们机构接受 MIS-TLIF 治疗的有症状腰椎退行性椎间盘病变患者的队列。我们比较了 MIS-TLIF 中使用可扩张 cage 与不可扩张 cage 的临床和影像学结果,重点是节段前凸、椎间盘高度的平均变化和术后并发症。结果与国际文献中报道的其他研究进行了比较。
两组之间节段前凸的平均变化没有显著差异。可扩张 cage 组术后沉降的发生率明显较高。
本研究表明,在单节段经椎间孔腰椎体间融合术中使用可扩张 cage 并不能降低术后并发症的发生率,反而显著增加了患者术后沉降的风险。与静态 cage 相比,可扩张 cage 目前没有显示出更好的临床结果或更好的矢状面排列。