Klinik und Poliklinik für Kardiologie, Universitätsklinikum Leipzig, Liebigstr. 20, 04103, Leipzig, Germany.
Institut für Medizinische Mikrobiologie und Virologie - Fachbereich Virologie, Universitätsklinikum Leipzig, Johannisallee 30, 04103, Leipzig, Germany.
Sci Rep. 2021 Sep 7;11(1):17798. doi: 10.1038/s41598-021-97120-x.
There is increasing evidence of cardiac involvement post-SARS-CoV-2 infections in symptomatic as well as in oligo- and asymptomatic athletes. This study aimed to characterize the possible early effects of SARS-CoV-2 infections on myocardial morphology and cardiopulmonary function in athletes. Eight male elite handball players (27 ± 3.5 y) with past SARS-CoV-2 infection were compared with four uninfected teammates (22 ± 2.6 y). Infected athletes were examined 19 ± 7 days after the first positive PCR test. Echocardiographic assessment of the global longitudinal strain under resting conditions was not significantly changed (- 17.7% vs. - 18.1%). However, magnetic resonance imaging showed minor signs of acute inflammation/oedema in all infected athletes (T2-mapping: + 4.1 ms, p = 0.034) without reaching the Lake-Louis criteria. Spiroergometric analysis showed a significant reduction in VO2max (- 292 ml/min, - 7.0%), oxygen pulse (- 2.4 ml/beat, - 10.4%), and respiratory minute volume (VE) (- 18.9 l/min, - 13.8%) in athletes with a history of SARS-CoV2 infection (p < 0.05, respectively). The parameters were unchanged in the uninfected teammates. SARS-CoV2 infection caused impairment of cardiopulmonary performance during physical effort in elite athletes. It seems reasonable to screen athletes after SARS-CoV2 infection with spiroergometry to identify performance limitations and to guide the return to competition.
越来越多的证据表明，在有症状和无症状的运动员中，SARS-CoV-2 感染后会出现心脏受累。本研究旨在描述 SARS-CoV-2 感染对运动员心肌形态和心肺功能的可能早期影响。8 名患有既往 SARS-CoV-2 感染的男性精英手球运动员（27±3.5 岁）与 4 名未感染的队友（22±2.6 岁）进行了比较。感染的运动员在第一次 PCR 检测呈阳性后 19±7 天进行了检查。在静息状态下，超声心动图评估的整体纵向应变没有显著变化（-17.7%比-18.1%）。然而，磁共振成像显示所有感染的运动员均有轻微的急性炎症/水肿迹象（T2 映射：+4.1ms，p=0.034），但未达到 Lake-Louis 标准。运动心肺功能分析显示，有 SARS-CoV2 感染史的运动员的 VO2max（-292ml/min，-7.0%）、氧脉冲（-2.4ml/beat，-10.4%）和呼吸分钟通气量（VE）（-18.9l/min，-13.8%）均显著降低（p<0.05）。未感染的队友的参数没有变化。SARS-CoV2 感染导致精英运动员在体力活动期间心肺功能受损。在手球运动员 SARS-CoV2 感染后进行运动心肺功能筛查以识别运动能力受限并指导重返比赛似乎是合理的。
