Sanger Heart and Vascular Institute, Atrium Health, Charlotte, North Carolina, USA.
Emory Clinical Cardiovascular Research Institute, Emory School of Medicine, Atlanta, Georgia, USA.
JACC Cardiovasc Imaging. 2020 Dec;13(12):2635-2652. doi: 10.1016/j.jcmg.2020.10.005. Epub 2020 Oct 28.
As our understanding of the complications of coronavirus disease-2019 (COVID-19) evolve, subclinical cardiac pathology such as myocarditis, pericarditis, and right ventricular dysfunction in the absence of significant clinical symptoms represents a concern. The potential implications of these findings in athletes are significant given the concern that exercise, during the acute phase of viral myocarditis, may exacerbate myocardial injury and precipitate malignant ventricular arrhythmias. Such concerns have led to the development and publication of expert consensus documents aimed at providing guidance for the evaluation of athletes after contracting COVID-19 in order to permit safe return to play. Cardiac imaging is at the center of these evaluations. This review seeks to evaluate the current evidence regarding COVID-19-associated cardiovascular disease and how multimodality imaging may be useful in the screening and clinical evaluation of athletes with suspected cardiovascular complications of infection. Guidance is provided with diagnostic "red flags" that raise the suspicion of pathology. Specific emphasis is placed on the unique challenges posed in distinguishing athletic cardiac remodeling from subclinical cardiac disease. The strengths and limitations of different imaging modalities are discussed and an approach to return to play decision making for athletes post-COVID-19, as informed by multimodality imaging, is provided.
随着我们对 2019 年冠状病毒病(COVID-19)并发症的认识不断发展,在没有明显临床症状的情况下,亚临床心脏病理学(如心肌炎、心包炎和右心室功能障碍)引起了关注。鉴于在病毒性心肌炎的急性期运动可能会加重心肌损伤并引发恶性室性心律失常,这些发现对运动员的潜在影响是重大的。这些担忧导致了专家共识文件的制定和发表,旨在为感染 COVID-19 后的运动员提供评估指导,以确保安全回归比赛。心脏成像处于这些评估的中心位置。本综述旨在评估与 COVID-19 相关的心血管疾病的现有证据,以及多模态成像如何在筛查和临床评估疑似感染引起的心血管并发症的运动员中发挥作用。提供了诊断“警示标志”,以提示存在病理学。特别强调了在区分运动性心脏重塑与亚临床心脏疾病方面所面临的独特挑战。讨论了不同成像方式的优缺点,并提供了一种基于多模态成像的 COVID-19 后运动员回归比赛的决策方法。