Universidade Federal de Pelotas, Pelotas, Brasil.
The University of Queensland, St. Lucia, Australia.
Cad Saude Publica. 2021 Aug 30;37(8):e00073320. doi: 10.1590/0102-311X00073320. eCollection 2021.
Brazil has the second highest age-standardized prevalence of Alzheimer's disease worldwide. However, information about Alzheimer's disease-related hospitalizations in Brazil is scarce despite its economic and social impact. We described temporal trends in hospitalizations related to Alzheimer's disease in Brazil from 2010 to 2019. We conducted a time-series, retrospective, descriptive, national-based study using data from the DATASUS database of the Brazilian Ministry of Health. Hospitalizations, mean days hospitalized, and economic costs from those hospitalizations were extracted from 2010 to 2019. Hospitalizations by Alzheimer's disease increased 87.7% from 2010 to 2019, with greater increase among men (97.4%), mixed ethnicity (224%), 80 years or older (115.1%), and in the Northeast (172.1%) and Central West (144.2%) regions. Although mean days hospitalized decreased in all subgroups, an increasing time trend in hospital admission was observed in the Central West Region. Costs per hospitalization increased for patients aged 50 years or younger and in admissions related to emergency services. Compared with other non-communicable chronic diseases, Alzheimer's disease had the highest increase in absolute number and rate of hospitalizations in Brazil from 2010 to 2019. AD is a public health problem in Brazil. Strategies to reduce its burden are necessary but only if accompanied by greater equality and awareness of this disease.
巴西是全球阿尔茨海默病年龄标准化患病率第二高的国家。然而，尽管该病对经济和社会造成了影响，但其相关住院信息却十分匮乏。我们描述了 2010 年至 2019 年巴西与阿尔茨海默病相关的住院趋势。我们使用巴西卫生部 DATASUS 数据库的数据，开展了一项基于全国的时间序列、回顾性、描述性研究。从 2010 年至 2019 年，我们提取了与阿尔茨海默病相关的住院人数、平均住院天数和经济成本。2010 年至 2019 年，阿尔茨海默病住院人数增加了 87.7%，其中男性（97.4%）、混血（224%）、80 岁及以上（115.1%）、东北地区（172.1%）和中西部地区（144.2%）的增幅更大。尽管所有亚组的平均住院天数都有所下降，但中西部地区的住院人数呈上升趋势。50 岁及以下患者和因急诊入院的患者的每次住院费用增加。与其他非传染性慢性疾病相比，2010 年至 2019 年，巴西阿尔茨海默病的住院人数绝对数和增长率最高。阿尔茨海默病是巴西的一个公共卫生问题。减少其负担的策略是必要的，但前提是必须伴随更大的平等和对这种疾病的认识。
